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- W4229695863 abstract "Canine impetigo is characterized by nonfollicular intraepidermal pustules that generally affect sparsely haired areas of the skin. This chapter aims to investigate the detailed mechanisms of staphylococcal invasion into living epidermis in a mouse model of impetigo. Three Staphylococcus aureus strains harbouring the etb gene (TY825,13 N1 and N2) as well as three strains negative for the three et genes (N3, N4 and N5) were used in the chapter. Identification of S. aureus was confirmed by a coagulase test and multiplex PCR was used to identify staphylococcal species. The findings presented in the chapter indicated that S. aureus harbouring the etb gene had invaded the interkeratinocyte clefts after neutrophils infiltrated the epidermis in this mouse model of impetigo. In addition, the dimensions of the interkeratinocyte spaces in mice inoculated with etb-gene positive strains increased over the time course analysed." @default.
- W4229695863 created "2022-05-11" @default.
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- W4229695863 date "2017-06-12" @default.
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- W4229695863 title "<i>Staphylococcus aureus</i>penetrate the interkeratinocyte spaces created by skin‐infiltrating neutrophils in a mouse model of impetigo" @default.
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- W4229695863 doi "https://doi.org/10.1002/9781119278368.ch5.5" @default.
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