Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229702961> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4229702961 endingPage "364" @default.
- W4229702961 startingPage "361" @default.
- W4229702961 abstract "Abstract Histological examination of endomyocardial biopsy (EMB) is the main technique for rejection surveillance after heart transplantation. This technique is elaborate, inconvenient for the patient, and not without complications. We prospectively analyzed whether the measurement of C-reactive protein (CRP), an acute phase protein that quickly rises when there is inflammation, can serve as a marker for immunological quiescence and as an indicator for withholding EMB. During a 6-month period, CRP was measured in all patients referred for EMB as part of the routine follow-up after heart transplantation. Acute rejection in patients with a follow-up of more than 1 year was rare (1/76). In the majority of cases, EMB was taken within the 1-year post-transplantation (170/246 = 69 %). In 71/170 biopsies (42 %), CRP was ≤ 1; in the other 99/170 (58%), CRP was ≥ 2. When CRP was ≤ 1, acute rejection was diagnosed in 12/70 cases (17%). In contrast, acute rejection was found in 28/99 cases (28%) with CRP ≥ 2 (P= 0.1). Although CRP is elevated more often in the presence of acute rejection, its sensitivity does not allow CRP to replace the routine performance of EMB for monitoring rejection after heart transplantation. We did, however, find a prognostic significance with regard to the effect of rejection treatment: in all acute rejections with a CRP ≤ 3 (n= 11), steroids were effective." @default.
- W4229702961 created "2022-05-11" @default.
- W4229702961 creator A5000354857 @default.
- W4229702961 creator A5008497236 @default.
- W4229702961 creator A5011538150 @default.
- W4229702961 creator A5044048234 @default.
- W4229702961 creator A5067828032 @default.
- W4229702961 creator A5083821618 @default.
- W4229702961 creator A5091881895 @default.
- W4229702961 date "1998-09-01" @default.
- W4229702961 modified "2023-09-26" @default.
- W4229702961 title "C-reactive protein in the monitoring of acute rejection after heart transplantation" @default.
- W4229702961 cites W1525476413 @default.
- W4229702961 cites W1910810396 @default.
- W4229702961 cites W1967052291 @default.
- W4229702961 cites W2023411218 @default.
- W4229702961 cites W2063906168 @default.
- W4229702961 cites W2071274843 @default.
- W4229702961 cites W2071317998 @default.
- W4229702961 cites W2127412241 @default.
- W4229702961 cites W2153391187 @default.
- W4229702961 doi "https://doi.org/10.1111/j.1432-2277.1998.tb00818.x" @default.
- W4229702961 hasPublicationYear "1998" @default.
- W4229702961 type Work @default.
- W4229702961 citedByCount "2" @default.
- W4229702961 crossrefType "journal-article" @default.
- W4229702961 hasAuthorship W4229702961A5000354857 @default.
- W4229702961 hasAuthorship W4229702961A5008497236 @default.
- W4229702961 hasAuthorship W4229702961A5011538150 @default.
- W4229702961 hasAuthorship W4229702961A5044048234 @default.
- W4229702961 hasAuthorship W4229702961A5067828032 @default.
- W4229702961 hasAuthorship W4229702961A5083821618 @default.
- W4229702961 hasAuthorship W4229702961A5091881895 @default.
- W4229702961 hasConcept C126322002 @default.
- W4229702961 hasConcept C141071460 @default.
- W4229702961 hasConcept C2775934546 @default.
- W4229702961 hasConcept C2776914184 @default.
- W4229702961 hasConcept C2778849806 @default.
- W4229702961 hasConcept C2781195455 @default.
- W4229702961 hasConcept C2911091166 @default.
- W4229702961 hasConcept C3019189323 @default.
- W4229702961 hasConcept C71924100 @default.
- W4229702961 hasConcept C90924648 @default.
- W4229702961 hasConceptScore W4229702961C126322002 @default.
- W4229702961 hasConceptScore W4229702961C141071460 @default.
- W4229702961 hasConceptScore W4229702961C2775934546 @default.
- W4229702961 hasConceptScore W4229702961C2776914184 @default.
- W4229702961 hasConceptScore W4229702961C2778849806 @default.
- W4229702961 hasConceptScore W4229702961C2781195455 @default.
- W4229702961 hasConceptScore W4229702961C2911091166 @default.
- W4229702961 hasConceptScore W4229702961C3019189323 @default.
- W4229702961 hasConceptScore W4229702961C71924100 @default.
- W4229702961 hasConceptScore W4229702961C90924648 @default.
- W4229702961 hasIssue "5" @default.
- W4229702961 hasLocation W42297029611 @default.
- W4229702961 hasOpenAccess W4229702961 @default.
- W4229702961 hasPrimaryLocation W42297029611 @default.
- W4229702961 hasRelatedWork W198116098 @default.
- W4229702961 hasRelatedWork W1987484775 @default.
- W4229702961 hasRelatedWork W1997755872 @default.
- W4229702961 hasRelatedWork W2072159497 @default.
- W4229702961 hasRelatedWork W2094589685 @default.
- W4229702961 hasRelatedWork W23877633 @default.
- W4229702961 hasRelatedWork W2417887465 @default.
- W4229702961 hasRelatedWork W2471253461 @default.
- W4229702961 hasRelatedWork W3033248215 @default.
- W4229702961 hasRelatedWork W3119668654 @default.
- W4229702961 hasVolume "11" @default.
- W4229702961 isParatext "false" @default.
- W4229702961 isRetracted "false" @default.
- W4229702961 workType "article" @default.