Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229758911> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4229758911 endingPage "441" @default.
- W4229758911 startingPage "439" @default.
- W4229758911 abstract "Characterisation of policosanol, a new active principle composed of 8 high molecular weight fatty alcohols, viz. 1-tetracosanol, 1-hexacosanol, 1-heptacosanol, 1-octacosanol, 1-nonacosanol, 1-triacontanol, 1-dotriacontanol, and 1-tetratriacontanol, shows it have a very stable, well defined composition which is reproducible from batch to batch. Compatibility studies by differential scanning calorimetry (DSC) and thermogravimetry (TG) gave very useful physicochemical information and reveal the characteristic transitions, as well as the thermal stability of this drug. DSC facilitated compatibility studies between policosanol and several tablet excipients generally used for the manufacture of this pharmaceutical dosage form. It is seen that the combination of policosanol with each excipient in every one of the ratios used did not produce any changes in the melting point of policosanol or those of the excipients mixed with it. Also, no new peaks were observed in the policosanol/excipient mixtures. It can be concluded from these results that no dissolution of policosanol in the excipients occurs, and also that no physicochemical interactions take place between them." @default.
- W4229758911 created "2022-05-11" @default.
- W4229758911 creator A5009797333 @default.
- W4229758911 creator A5044908281 @default.
- W4229758911 creator A5045841758 @default.
- W4229758911 date "1999-12-01" @default.
- W4229758911 modified "2023-09-30" @default.
- W4229758911 title "Characterization and Compatibility Studies between Policosanol, a New Hypocholesterolemic Drug, and Tablet Excipients Using Differential Scanning Calorimetry (DSC)" @default.
- W4229758911 doi "https://doi.org/10.1002/(sici)1521-4184(199912)332:12<439::aid-ardp439>3.3.co;2-x" @default.
- W4229758911 hasPublicationYear "1999" @default.
- W4229758911 type Work @default.
- W4229758911 citedByCount "0" @default.
- W4229758911 crossrefType "journal-article" @default.
- W4229758911 hasAuthorship W4229758911A5009797333 @default.
- W4229758911 hasAuthorship W4229758911A5044908281 @default.
- W4229758911 hasAuthorship W4229758911A5045841758 @default.
- W4229758911 hasConcept C121332964 @default.
- W4229758911 hasConcept C127413603 @default.
- W4229758911 hasConcept C179104552 @default.
- W4229758911 hasConcept C185592680 @default.
- W4229758911 hasConcept C2777239854 @default.
- W4229758911 hasConcept C2778648169 @default.
- W4229758911 hasConcept C39519442 @default.
- W4229758911 hasConcept C39588626 @default.
- W4229758911 hasConcept C42360764 @default.
- W4229758911 hasConcept C43617362 @default.
- W4229758911 hasConcept C77281830 @default.
- W4229758911 hasConcept C97355855 @default.
- W4229758911 hasConceptScore W4229758911C121332964 @default.
- W4229758911 hasConceptScore W4229758911C127413603 @default.
- W4229758911 hasConceptScore W4229758911C179104552 @default.
- W4229758911 hasConceptScore W4229758911C185592680 @default.
- W4229758911 hasConceptScore W4229758911C2777239854 @default.
- W4229758911 hasConceptScore W4229758911C2778648169 @default.
- W4229758911 hasConceptScore W4229758911C39519442 @default.
- W4229758911 hasConceptScore W4229758911C39588626 @default.
- W4229758911 hasConceptScore W4229758911C42360764 @default.
- W4229758911 hasConceptScore W4229758911C43617362 @default.
- W4229758911 hasConceptScore W4229758911C77281830 @default.
- W4229758911 hasConceptScore W4229758911C97355855 @default.
- W4229758911 hasIssue "12" @default.
- W4229758911 hasLocation W42297589111 @default.
- W4229758911 hasOpenAccess W4229758911 @default.
- W4229758911 hasPrimaryLocation W42297589111 @default.
- W4229758911 hasRelatedWork W1975654110 @default.
- W4229758911 hasRelatedWork W2003427276 @default.
- W4229758911 hasRelatedWork W2041604651 @default.
- W4229758911 hasRelatedWork W2045973997 @default.
- W4229758911 hasRelatedWork W2066729486 @default.
- W4229758911 hasRelatedWork W2087953915 @default.
- W4229758911 hasRelatedWork W2094432352 @default.
- W4229758911 hasRelatedWork W4229758911 @default.
- W4229758911 hasRelatedWork W44910325 @default.
- W4229758911 hasRelatedWork W992412571 @default.
- W4229758911 hasVolume "332" @default.
- W4229758911 isParatext "false" @default.
- W4229758911 isRetracted "false" @default.
- W4229758911 workType "article" @default.