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- W4229848247 abstract "Purpose The aim of the Heartmate (HM) XVE Opti-Fill software is to reduce the incidence of high blood chamber and inflow valve peak pressure pulses and to reduce the stress at interior parts of the pump as compared to the HM VE. We investigated this claim in a clinical comparison. Methods The relation between Stroke Volume (SV) and peak pressure pulses was investigated using a Circulatory Mock Loop, controlling SV’s at afterloads from 50 - 130 mmHg. We measured Blood Chamber Peak Pressure (BCPP) and Inflow Valve Peak Pressure (IVPP). The distribution of SV’s was registered in 2 VE and 6 XVE patients during rest and Activities of Daily Living (ADL). Results At high SV’s, 79 - 83 ml, BCPP and IVPP never exceeded 400 mmHg. BCPP and IVPP started to increase when SV was reduced to 78 ml. Maximum peak pressures occured at a SV of 50 ml: 788 for BCPP and 416 for IVPP. The pressures depended on the resistance and compliance of the HM and Mock Loop. For clinical comparison, percentages of SV > 78 ml were determined. Conclusion Use of Opti-Fill software shows a significant increase in percentage SV’s > 78 ml thereby reducing the incidence of high peak pressure pulses. This might diminish inflow valve damage and stress at interior parts of the pump in the clinical setting.Table: Percentage SV > 78 ml" @default.
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- W4229848247 date "2005-03-01" @default.
- W4229848247 modified "2023-09-27" @default.
- W4229848247 title "CLINICAL COMPARISON BETWEEN HEARTMATE VE AUTO MODE AND HEARTMATE XVE OPTI-FILL AND THE EFFECT OF STROKE VOLUME AT BLOOD CHAMBER AND INFLOW VALVE PEAK PRESSURES" @default.
- W4229848247 doi "https://doi.org/10.1097/00002480-200503000-00138" @default.
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