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- W4229924982 abstract "Mutation of genes of the nitrogen related phosphotransferase system, PTSNtr, causes pleiotropic phenotypes in a wide range of bacteria. While a clear link to nitrogen metabolism is lacking, regulatory function in potassium homeostasis, via the regulation of K+ transport systems has been demonstrated in Escherichia coli and Rhizobium leguminosarum. Here we report that PTSNtr is also required for a full activation of ABC transport activities in R. leguminosarum. Additionally, we identify the typical organisation of PTSNtr components in α-proteobacteria and discuss key components of their regulation. We also demonstrate that under strong K+ limitation PTSNtr reduces ABC transport. This is achieved by the inverse regulation of two important ATP dependent transporter classes." @default.
- W4229924982 created "2022-05-11" @default.
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- W4229924982 date "2015-07-14" @default.
- W4229924982 modified "2023-09-24" @default.
- W4229924982 title "The PTS <sup>Ntr</sup> System Globally Regulates ATP‐Dependent Transporters in <i>Rhizobium leguminosarum</i>" @default.
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- W4229924982 doi "https://doi.org/10.1002/9781119053095.ch34" @default.
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