Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229998392> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4229998392 abstract "Mol. Nutr. Food Res. 2021, 65, 2001065 DOI: 10.1002/mnfr.202001065 Citrobacter rodentium (C. rodentium) is a well described murine pathogen that closely resembles human diarrheal pathogens enteropathogenic Escherichia coli (E. coli.) and enterohaemorrhagic E. coli. Adherent C. rodentium adapt to the gastrointestinal environment and undergo a virulence switch that facilitates colonization of the distal colon. The virulence proteins produced by C. rodentium lead to breakdown of the intestinal tight junction proteins and apoptosis of the intestinal epithelial cells, which enables permeation of C. rodentium into the lamina propria. Recognition of C. rodentium by the lamina propria immune cells initiates the mucosal inflammatory responses, including of secretion of pro-inflammatory cytokines and infiltration of immune cells themselves in the colonic epithelium. Supplementation with glycine restores the integrity of the colonic epithelium by upregulating tight junction protein expression and inhibiting of intestinal epithelial cell apoptosis, thus suppressing the overactivated inflammatory responses. Supplementation with glycine is a nutritional strategy to alleviate C. rodentium-induced colitis in mice. This is reported by Zhenlong Wu and co-workes in article number 2001065." @default.
- W4229998392 created "2022-05-11" @default.
- W4229998392 creator A5000481169 @default.
- W4229998392 creator A5007877359 @default.
- W4229998392 creator A5023558826 @default.
- W4229998392 creator A5037521007 @default.
- W4229998392 creator A5047171623 @default.
- W4229998392 creator A5059997287 @default.
- W4229998392 creator A5070473172 @default.
- W4229998392 creator A5083868441 @default.
- W4229998392 creator A5084300536 @default.
- W4229998392 creator A5090392492 @default.
- W4229998392 date "2021-08-01" @default.
- W4229998392 modified "2023-10-17" @default.
- W4229998392 title "Back Cover: Glycine Attenuates Citrobacter rodentium ‐Induced Colitis by Regulating ATF6‐Mediated Endoplasmic Reticulum Stress in Mice" @default.
- W4229998392 doi "https://doi.org/10.1002/mnfr.202170039" @default.
- W4229998392 hasPublicationYear "2021" @default.
- W4229998392 type Work @default.
- W4229998392 citedByCount "0" @default.
- W4229998392 crossrefType "journal-article" @default.
- W4229998392 hasAuthorship W4229998392A5000481169 @default.
- W4229998392 hasAuthorship W4229998392A5007877359 @default.
- W4229998392 hasAuthorship W4229998392A5023558826 @default.
- W4229998392 hasAuthorship W4229998392A5037521007 @default.
- W4229998392 hasAuthorship W4229998392A5047171623 @default.
- W4229998392 hasAuthorship W4229998392A5059997287 @default.
- W4229998392 hasAuthorship W4229998392A5070473172 @default.
- W4229998392 hasAuthorship W4229998392A5083868441 @default.
- W4229998392 hasAuthorship W4229998392A5084300536 @default.
- W4229998392 hasAuthorship W4229998392A5090392492 @default.
- W4229998392 hasConcept C104317684 @default.
- W4229998392 hasConcept C126322002 @default.
- W4229998392 hasConcept C177779419 @default.
- W4229998392 hasConcept C203014093 @default.
- W4229998392 hasConcept C2775862500 @default.
- W4229998392 hasConcept C2775945818 @default.
- W4229998392 hasConcept C2776460866 @default.
- W4229998392 hasConcept C2777310793 @default.
- W4229998392 hasConcept C2778910516 @default.
- W4229998392 hasConcept C2910319489 @default.
- W4229998392 hasConcept C3019368612 @default.
- W4229998392 hasConcept C49039625 @default.
- W4229998392 hasConcept C529295009 @default.
- W4229998392 hasConcept C54355233 @default.
- W4229998392 hasConcept C547475151 @default.
- W4229998392 hasConcept C55493867 @default.
- W4229998392 hasConcept C60987743 @default.
- W4229998392 hasConcept C71924100 @default.
- W4229998392 hasConcept C86803240 @default.
- W4229998392 hasConcept C8891405 @default.
- W4229998392 hasConcept C89423630 @default.
- W4229998392 hasConcept C95444343 @default.
- W4229998392 hasConceptScore W4229998392C104317684 @default.
- W4229998392 hasConceptScore W4229998392C126322002 @default.
- W4229998392 hasConceptScore W4229998392C177779419 @default.
- W4229998392 hasConceptScore W4229998392C203014093 @default.
- W4229998392 hasConceptScore W4229998392C2775862500 @default.
- W4229998392 hasConceptScore W4229998392C2775945818 @default.
- W4229998392 hasConceptScore W4229998392C2776460866 @default.
- W4229998392 hasConceptScore W4229998392C2777310793 @default.
- W4229998392 hasConceptScore W4229998392C2778910516 @default.
- W4229998392 hasConceptScore W4229998392C2910319489 @default.
- W4229998392 hasConceptScore W4229998392C3019368612 @default.
- W4229998392 hasConceptScore W4229998392C49039625 @default.
- W4229998392 hasConceptScore W4229998392C529295009 @default.
- W4229998392 hasConceptScore W4229998392C54355233 @default.
- W4229998392 hasConceptScore W4229998392C547475151 @default.
- W4229998392 hasConceptScore W4229998392C55493867 @default.
- W4229998392 hasConceptScore W4229998392C60987743 @default.
- W4229998392 hasConceptScore W4229998392C71924100 @default.
- W4229998392 hasConceptScore W4229998392C86803240 @default.
- W4229998392 hasConceptScore W4229998392C8891405 @default.
- W4229998392 hasConceptScore W4229998392C89423630 @default.
- W4229998392 hasConceptScore W4229998392C95444343 @default.
- W4229998392 hasIssue "15" @default.
- W4229998392 hasLocation W42299983921 @default.
- W4229998392 hasOpenAccess W4229998392 @default.
- W4229998392 hasPrimaryLocation W42299983921 @default.
- W4229998392 hasRelatedWork W1990473825 @default.
- W4229998392 hasRelatedWork W1993858609 @default.
- W4229998392 hasRelatedWork W2065214355 @default.
- W4229998392 hasRelatedWork W2097818551 @default.
- W4229998392 hasRelatedWork W2466290589 @default.
- W4229998392 hasRelatedWork W2556202785 @default.
- W4229998392 hasRelatedWork W2883253746 @default.
- W4229998392 hasRelatedWork W3134638538 @default.
- W4229998392 hasRelatedWork W4229998392 @default.
- W4229998392 hasRelatedWork W4252777136 @default.
- W4229998392 hasVolume "65" @default.
- W4229998392 isParatext "false" @default.
- W4229998392 isRetracted "false" @default.
- W4229998392 workType "article" @default.