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- W4230000003 abstract "<h3>To the Editor.—</h3> The advice of the consultant on the best treatment for recurrent cystitis (236:2546, 1976) contains some important errors. According to the reply, the optimal treatment for cystitis is one to three months of antibiotic therapy. While prolonged antibiotic therapy may be necessary for relapsing pyelonephritis, most cases of chronic cystitis are really reinfections.<sup>1</sup>The therapeutic problem lies not in sterilizing the urine, which can be done with a short course of an appropriate antibiotic (235:1854, 1976), but in preventing reinfection. It is stated that the entrance of bacteria into the bladder during bathing is an important factor in producing cystitis. Introducing bacteria in large titers into the bladders of normal humans has not produced cystitis or pyuria, and the urine has been sterilized spontaneously within 72 hours.<sup>2</sup>A compromise of the bladder's defense to bacterial invasion is undoubtedly important in the pathogenesis of" @default.
- W4230000003 created "2022-05-11" @default.
- W4230000003 date "1977-06-27" @default.
- W4230000003 modified "2023-10-14" @default.
- W4230000003 doi "https://doi.org/10.1001/jama.237.26.2813" @default.
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