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- W4230082554 abstract "This chapter presents a general overview of the antiepileptic drugs through several case studies to illustrate the effects of antiepileptic drugs on the nervous system and endocrine systems. It also discusses immunological and hypersensitivity reactions and the risk factors associated with antiepileptic drugs and reviews various individual drugs and their effects on different body systems and body parts. Serious hypersensitivity reactions to gabapentin are extremely rare. Insomnia is a recognized adverse effect of lamotrigine. In a placebo-controlled study in healthy women, oxcarbazepine reduced the serum concentrations of ethinylestradiol and levonorgestrel by about 50%. This confirms that oxcarbazepine may reduce the efficacy of the contraceptive pill, similarly to carbamazepine. Slowed mental function is a relatively common adverse effect of topiramate, especially at high dosages, and has been confirmed in a randomized single-blind parallel-group study in healthy volunteers. After single doses, topiramate reduces performance in attention and word fluency tests, whereas lamotrigine and gabapentin have no effects." @default.
- W4230082554 created "2022-05-11" @default.
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- W4230082554 date "2000-01-01" @default.
- W4230082554 modified "2023-09-27" @default.
- W4230082554 title "Antiepileptic drugs" @default.
- W4230082554 doi "https://doi.org/10.1016/s0378-6080(00)80013-6" @default.
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