Matches in SemOpenAlex for { <https://semopenalex.org/work/W4230394519> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4230394519 endingPage "951" @default.
- W4230394519 startingPage "948" @default.
- W4230394519 abstract "We have examined the effect of tubal sterilisation and hysterectomy on risk of ovarian cancer in a large case-control study in eastern Australia involving 824 women aged 18-79 years, diagnosed with epithelial ovarian cancer between 1990 and 1993, and 855 controls randomly selected from the electoral roll. Relative risks for ovarian cancer were estimated using multiple categorical regression to adjust for age, parity, oral contraceptive use and other risk factors. Tubal sterilisation was associated with a 39% reduction in risk of ovarian cancer (RR 0.61, 95% CI 0.46-0.85) and hysterectomy with a 36%reduction (RR 0.64, 95%CI 0.48-0.85). Risk remained low 25 years after surgery and was reduced irrespective of sterilisation technique, and estimates were similar among various types of epithelial ovarian cancer. The greatest reduction (74%) was observed among women with primary peritoneal tumours. Pelvic infection and use of vaginal sprays or contraceptive foams were not related to ovarian cancer, while use of talc in the perineal region slightly but significantly increased risk among women with patent fallopian tubes. Reportedly heavy or painful menses, perhaps associated with retrograde flow, were associated with ovarian cancer, and reduction in risk of disease after hysterectomy was greatest among women who had heavy periods. Our findings support the theory that contaminants from the vagina, such as talc, and from the uterus, such as endometrium, gain access to the peritoneal cavity through patent fallopian tubes and may enhance the malignant transformation of ovarian surface epithelium. Surgical tubal occlusion may reduce the risk of ovarian cancer by preventing the access of such agents. Int. J. Cancer 71: 948-951, 1997. © 1997 Wiley-Liss Inc." @default.
- W4230394519 created "2022-05-11" @default.
- W4230394519 creator A5003226234 @default.
- W4230394519 creator A5044266157 @default.
- W4230394519 creator A5044583406 @default.
- W4230394519 creator A5046500631 @default.
- W4230394519 creator A5049964188 @default.
- W4230394519 creator A5052124757 @default.
- W4230394519 creator A5056039037 @default.
- W4230394519 date "1997-06-11" @default.
- W4230394519 modified "2023-10-16" @default.
- W4230394519 title "Tubal sterilisation, hysterectomy and decreased risk of ovarian cancer" @default.
- W4230394519 doi "https://doi.org/10.1002/(sici)1097-0215(19970611)71:6<948::aid-ijc6>3.3.co;2-9" @default.
- W4230394519 hasPublicationYear "1997" @default.
- W4230394519 type Work @default.
- W4230394519 citedByCount "9" @default.
- W4230394519 crossrefType "journal-article" @default.
- W4230394519 hasAuthorship W4230394519A5003226234 @default.
- W4230394519 hasAuthorship W4230394519A5044266157 @default.
- W4230394519 hasAuthorship W4230394519A5044583406 @default.
- W4230394519 hasAuthorship W4230394519A5046500631 @default.
- W4230394519 hasAuthorship W4230394519A5049964188 @default.
- W4230394519 hasAuthorship W4230394519A5052124757 @default.
- W4230394519 hasAuthorship W4230394519A5056039037 @default.
- W4230394519 hasBestOaLocation W42303945191 @default.
- W4230394519 hasConcept C121608353 @default.
- W4230394519 hasConcept C126322002 @default.
- W4230394519 hasConcept C131872663 @default.
- W4230394519 hasConcept C141071460 @default.
- W4230394519 hasConcept C2775883341 @default.
- W4230394519 hasConcept C2777088508 @default.
- W4230394519 hasConcept C2779066055 @default.
- W4230394519 hasConcept C2779494336 @default.
- W4230394519 hasConcept C2780427987 @default.
- W4230394519 hasConcept C29456083 @default.
- W4230394519 hasConcept C44249647 @default.
- W4230394519 hasConcept C71924100 @default.
- W4230394519 hasConcept C82789193 @default.
- W4230394519 hasConceptScore W4230394519C121608353 @default.
- W4230394519 hasConceptScore W4230394519C126322002 @default.
- W4230394519 hasConceptScore W4230394519C131872663 @default.
- W4230394519 hasConceptScore W4230394519C141071460 @default.
- W4230394519 hasConceptScore W4230394519C2775883341 @default.
- W4230394519 hasConceptScore W4230394519C2777088508 @default.
- W4230394519 hasConceptScore W4230394519C2779066055 @default.
- W4230394519 hasConceptScore W4230394519C2779494336 @default.
- W4230394519 hasConceptScore W4230394519C2780427987 @default.
- W4230394519 hasConceptScore W4230394519C29456083 @default.
- W4230394519 hasConceptScore W4230394519C44249647 @default.
- W4230394519 hasConceptScore W4230394519C71924100 @default.
- W4230394519 hasConceptScore W4230394519C82789193 @default.
- W4230394519 hasIssue "6" @default.
- W4230394519 hasLocation W42303945191 @default.
- W4230394519 hasOpenAccess W4230394519 @default.
- W4230394519 hasPrimaryLocation W42303945191 @default.
- W4230394519 hasRelatedWork W1944154694 @default.
- W4230394519 hasRelatedWork W1988990531 @default.
- W4230394519 hasRelatedWork W2027402251 @default.
- W4230394519 hasRelatedWork W2111573842 @default.
- W4230394519 hasRelatedWork W2113948424 @default.
- W4230394519 hasRelatedWork W2734526255 @default.
- W4230394519 hasRelatedWork W2810862141 @default.
- W4230394519 hasRelatedWork W2963330805 @default.
- W4230394519 hasRelatedWork W2964804582 @default.
- W4230394519 hasRelatedWork W4290328035 @default.
- W4230394519 hasVolume "71" @default.
- W4230394519 isParatext "false" @default.
- W4230394519 isRetracted "false" @default.
- W4230394519 workType "article" @default.