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- W4230487659 abstract "Alkyne metathesis is increasingly explored as a reliable method to close macrocyclic rings, but there are no prior examples of an alkyne-metathesis-based homodimerization approach to natural products. In this approach to the cytotoxic C2-symmetric marine-derived bis(lactone) disorazole C1, a highly convergent, modular strategy is employed featuring cyclization through an ambitious one-pot alkyne cross-metathesis/ring-closing metathesis self-assembly process." @default.
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- W4230487659 date "2015-04-29" @default.
- W4230487659 modified "2023-10-13" @default.
- W4230487659 title "Self-Assembly of Disorazole C<sub>1</sub>through a One-Pot Alkyne Metathesis Homodimerization Strategy" @default.
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- W4230487659 doi "https://doi.org/10.1002/ange.201501922" @default.
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