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- W4230590412 abstract "The calculation of probabilities on pedigrees of arbitrary complexity is discussed for a basic model of transmission and penetrance (encompassing Mendelian inheritance, and certain environmental influences). The structure of pedigrees, and the types of loops occurring, is discussed. Some results in graph theory are obtained and, using these, a recurrence relation derived for certain probabilities. The recursive procedure enables the successive peeling off of certain members of the pedigree, and the condensation of the information on those individuals into a function on a subset of those remaining. The underlying theory is set out, and examples given of the utilization of the resulting algorithm." @default.
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- W4230590412 date "1978-03-01" @default.
- W4230590412 modified "2023-10-18" @default.
- W4230590412 title "Probability functions on complex pedigrees" @default.
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- W4230590412 doi "https://doi.org/10.1017/s0001867800029475" @default.
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