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• W4230998952 abstract "Each year in the United States alone there are about 1 million “heart attacks”—a term that includes both acute infarction and sudden cardiac death. 1 Braunwald E Friedewald WT Furberg CF Proceedings of the workshop on platelet-active drugs in the secondary prevention of cardiovascular events. Circulation. 1980; 62: 6 Google Scholar , 2 Hurst JW Logue RB Walter PF The clinical recognition and management of coronary atherosclerotic heart disease. in: Hurst JW Logue RB Schlant RC The heart, arteries, and veins. McGraw-Hill Book Co, New York1978: 1216-1219 Google Scholar , 3 Weinblatt E Shapiro S Frank CW et al. Prognosis of men after myocardial infarction: mortality and first recurrence in relation to selected parameters. Am J Public Health. 1968; 58: 1329-1347 Crossref Scopus (148) Google Scholar , 4 Kannel WG Thomas HE Sudden coronary death: the Framingham study. Ann NY Acad Sci. 1982; 382: 3-21 Crossref PubMed Scopus (193) Google Scholar Nearly 300,000 victims die before admission to the hospital, and about another 200,000 die in the first month, most of them in the first 24 hours after the attack. Thus, the cumulative mortality during the first month is about 50%. During the next six months, the cumulative mortality increases another 7-8%, so that by one year, another 10% have died. 1 Braunwald E Friedewald WT Furberg CF Proceedings of the workshop on platelet-active drugs in the secondary prevention of cardiovascular events. Circulation. 1980; 62: 6 Google Scholar , 2 Hurst JW Logue RB Walter PF The clinical recognition and management of coronary atherosclerotic heart disease. in: Hurst JW Logue RB Schlant RC The heart, arteries, and veins. McGraw-Hill Book Co, New York1978: 1216-1219 Google Scholar , 5 Beard OW Hipp HR Robins M et al. Initial myocardial infarction among 503 veterans: five-year survival. Am J Med. 1960; 28: 871-883 Abstract Full Text PDF PubMed Scopus (54) Google Scholar This means that, of the 400,000-500,000 patients who survive the first month, about 10% (40,000-50,000) die during the first year following infarction, generally due to sudden death or recurrent infarction. After patients have survived a year, the reinfarction and death rate stabilizes at 3-5% per year. This rate is similar to that of patients with symptomatic coronary artery disease (ie, angina pectoris) but is significantly greater than that of a randomly selected, age-matched population without overt coronary artery disease that has a 1% yearly incidence of those events. 3 Weinblatt E Shapiro S Frank CW et al. Prognosis of men after myocardial infarction: mortality and first recurrence in relation to selected parameters. Am J Public Health. 1968; 58: 1329-1347 Crossref Scopus (148) Google Scholar , 6 Report from the Committee of Principal Investigators. A cooperative trial in the primary prevention of ischaemic heart disease using clofibrate. Br Heart J. 1978; 40: 1069-1118 Crossref PubMed Scopus (841) Google Scholar" @default.
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• W4230998952 date "1986-02-01" @default.
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• W4230998952 title "Antithrombotic Agents in Coronary Artery Disease" @default.
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