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• W4231439398 abstract "<sec> <title>BACKGROUND</title> Automated insulin delivery (AID) systems have been shown to be safe and effective in reducing hyperglycemia and hypoglycemia but are not universally available, accessible, or affordable. Therefore, user-driven open-source AID systems are becoming increasingly popular. </sec> <sec> <title>OBJECTIVE</title> This study aims to investigate the motivations for which people with diabetes (types 1, 2, and other) or their caregivers decide to build and use a personalized open-source AID. </sec> <sec> <title>METHODS</title> A cross-sectional web-based survey was conducted to assess personal motivations and associated self-reported clinical outcomes. </sec> <sec> <title>RESULTS</title> Of 897 participants from 35 countries, 80.5% (722) were adults with diabetes and 19.5% (175) were caregivers of children with diabetes. Primary motivations to commence open-source AID included improving glycemic outcomes (476/509 adults, 93.5%, and 95/100 caregivers, 95%), reducing acute (443/508 adults, 87.2%, and 96/100 caregivers, 96%) and long-term (421/505 adults, 83.3%, and 91/100 caregivers, 91%) complication risk, interacting less frequently with diabetes technology (413/509 adults, 81.1%; 86/100 caregivers, 86%), improving their or child’s sleep quality (364/508 adults, 71.6%, and 80/100 caregivers, 80%), increasing their or child’s life expectancy (381/507 adults, 75.1%, and 84/100 caregivers, 84%), lack of commercially available AID systems (359/507 adults, 70.8%, and 79/99 caregivers, 80%), and unachieved therapy goals with available therapy options (348/509 adults, 68.4%, and 69/100 caregivers, 69%). Improving their own sleep quality was an almost universal motivator for caregivers (94/100, 94%). Significant improvements, independent of age and gender, were observed in self-reported glycated hemoglobin (HbA_1c), 7.14% (SD 1.13%; 54.5 mmol/mol, SD 12.4) to 6.24% (SD 0.64%; 44.7 mmol/mol, SD 7.0; <i>P</i>&lt;.001), and time in range (62.96%, SD 16.18%, to 80.34%, SD 9.41%; <i>P</i>&lt;.001). </sec> <sec> <title>CONCLUSIONS</title> These results highlight the unmet needs of people with diabetes, provide new insights into the evolving phenomenon of open-source AID technology, and indicate improved clinical outcomes. This study may inform health care professionals and policy makers about the opportunities provided by open-source AID systems. </sec> <sec> <title>CLINICALTRIAL</title> <p /> </sec> <sec> <title>INTERNATIONAL REGISTERED REPORT</title> RR2-10.2196/15368 </sec>" @default.
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• W4231439398 date "2020-10-31" @default.
• W4231439398 modified "2023-09-27" @default.
• W4231439398 title "Why #WeAreNotWaiting—Motivations and Self-Reported Outcomes Among Users of Open-source Automated Insulin Delivery Systems: Multinational Survey (Preprint)" @default.
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• W4231439398 doi "https://doi.org/10.2196/preprints.25409" @default.
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