Matches in SemOpenAlex for { <https://semopenalex.org/work/W4231449757> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4231449757 abstract "The existence of eukaryotic ribosomes with distinct ribosomal protein (RP) stoichiometry and regulatory roles in protein synthesis been speculated for over sixty years. Recent advances in mass spectrometry and high throughput analysis have begun to identify and characterize distinct ribosome stoichiometry in yeast or mammalian systems. In addition to RP stoichiometry, ribosomes play host to a vast array of protein modifications, effectively expanding the number of human RPs from 80 to many thousands of distinct proteoforms. Is it possible these proteoforms combine to function as a ‘ribosome code’ to tune protein synthesis? We outline the specific benefits that translational regulation by specialized ribosomes can offer and discuss the means and methodologies available to correlate and characterize RP stoichiometry with function. We highlight previous research with a focus on formulating hypotheses that can guide future experiments and crack the ‘ribosome code’." @default.
- W4231449757 created "2022-05-12" @default.
- W4231449757 creator A5059881489 @default.
- W4231449757 creator A5067445892 @default.
- W4231449757 creator A5076838113 @default.
- W4231449757 date "2018-06-15" @default.
- W4231449757 modified "2023-09-27" @default.
- W4231449757 title "Ribosome stoichiometry: from form to function." @default.
- W4231449757 doi "https://doi.org/10.7287/peerj.preprints.26991v1" @default.
- W4231449757 hasPublicationYear "2018" @default.
- W4231449757 type Work @default.
- W4231449757 citedByCount "4" @default.
- W4231449757 countsByYear W42314497572017 @default.
- W4231449757 countsByYear W42314497572018 @default.
- W4231449757 countsByYear W42314497572019 @default.
- W4231449757 countsByYear W42314497572023 @default.
- W4231449757 crossrefType "posted-content" @default.
- W4231449757 hasAuthorship W4231449757A5059881489 @default.
- W4231449757 hasAuthorship W4231449757A5067445892 @default.
- W4231449757 hasAuthorship W4231449757A5076838113 @default.
- W4231449757 hasBestOaLocation W42314497571 @default.
- W4231449757 hasConcept C104317684 @default.
- W4231449757 hasConcept C105580179 @default.
- W4231449757 hasConcept C129194359 @default.
- W4231449757 hasConcept C14036430 @default.
- W4231449757 hasConcept C144082473 @default.
- W4231449757 hasConcept C149364088 @default.
- W4231449757 hasConcept C178790620 @default.
- W4231449757 hasConcept C182325514 @default.
- W4231449757 hasConcept C185592680 @default.
- W4231449757 hasConcept C3675279 @default.
- W4231449757 hasConcept C54355233 @default.
- W4231449757 hasConcept C67705224 @default.
- W4231449757 hasConcept C67905577 @default.
- W4231449757 hasConcept C70721500 @default.
- W4231449757 hasConcept C86803240 @default.
- W4231449757 hasConcept C88478588 @default.
- W4231449757 hasConcept C95444343 @default.
- W4231449757 hasConceptScore W4231449757C104317684 @default.
- W4231449757 hasConceptScore W4231449757C105580179 @default.
- W4231449757 hasConceptScore W4231449757C129194359 @default.
- W4231449757 hasConceptScore W4231449757C14036430 @default.
- W4231449757 hasConceptScore W4231449757C144082473 @default.
- W4231449757 hasConceptScore W4231449757C149364088 @default.
- W4231449757 hasConceptScore W4231449757C178790620 @default.
- W4231449757 hasConceptScore W4231449757C182325514 @default.
- W4231449757 hasConceptScore W4231449757C185592680 @default.
- W4231449757 hasConceptScore W4231449757C3675279 @default.
- W4231449757 hasConceptScore W4231449757C54355233 @default.
- W4231449757 hasConceptScore W4231449757C67705224 @default.
- W4231449757 hasConceptScore W4231449757C67905577 @default.
- W4231449757 hasConceptScore W4231449757C70721500 @default.
- W4231449757 hasConceptScore W4231449757C86803240 @default.
- W4231449757 hasConceptScore W4231449757C88478588 @default.
- W4231449757 hasConceptScore W4231449757C95444343 @default.
- W4231449757 hasLocation W42314497571 @default.
- W4231449757 hasOpenAccess W4231449757 @default.
- W4231449757 hasPrimaryLocation W42314497571 @default.
- W4231449757 hasRelatedWork W1965544421 @default.
- W4231449757 hasRelatedWork W1981332340 @default.
- W4231449757 hasRelatedWork W2077554656 @default.
- W4231449757 hasRelatedWork W2302417020 @default.
- W4231449757 hasRelatedWork W2891079928 @default.
- W4231449757 hasRelatedWork W2982044300 @default.
- W4231449757 hasRelatedWork W2993746750 @default.
- W4231449757 hasRelatedWork W3011315026 @default.
- W4231449757 hasRelatedWork W3157874904 @default.
- W4231449757 hasRelatedWork W4361225311 @default.
- W4231449757 isParatext "false" @default.
- W4231449757 isRetracted "false" @default.
- W4231449757 workType "article" @default.