Matches in SemOpenAlex for { <https://semopenalex.org/work/W4231520204> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W4231520204 endingPage "295" @default.
- W4231520204 startingPage "288" @default.
- W4231520204 abstract "Precise genome duplication requires accurate copying by DNA polymerases and the elimination of occasional mistakes by proofreading exonucleases and mismatch repair enzymes. The commonly held belief that ‘if something is worth doing, then it's worth doing well’ normally applies to DNA replication and repair, however, there are exceptions. This review describes elements that are crucial to cell fitness, evolution and survival in the recently discovered error-prone DNA polymerases. Large numbers of errant DNA polymerases, spanning microorganisms to humans, are used to rescue stalled replication forks by copying damaged DNA and even undamaged DNA to generate ‘purposeful’ mutations that generate genetic diversity in times of stress. Here we focus on low-fidelity polymerases from bacteria, comparing Escherichia coli, archeabacteria and those most recently discovered in Gram-positive Bacilli, Streptococcus, pathogenic Mycobacterium and intein-containing cyanobacteria." @default.
- W4231520204 created "2022-05-12" @default.
- W4231520204 creator A5081248010 @default.
- W4231520204 date "2004-06-01" @default.
- W4231520204 modified "2023-09-26" @default.
- W4231520204 title "Error-prone replication for better or worse" @default.
- W4231520204 doi "https://doi.org/10.1016/s0966-842x(04)00095-2" @default.
- W4231520204 hasPublicationYear "2004" @default.
- W4231520204 type Work @default.
- W4231520204 citedByCount "0" @default.
- W4231520204 crossrefType "journal-article" @default.
- W4231520204 hasAuthorship W4231520204A5081248010 @default.
- W4231520204 hasConcept C170748874 @default.
- W4231520204 hasConcept C2756471 @default.
- W4231520204 hasConcept C54355233 @default.
- W4231520204 hasConcept C552990157 @default.
- W4231520204 hasConcept C70721500 @default.
- W4231520204 hasConcept C73573662 @default.
- W4231520204 hasConcept C82381507 @default.
- W4231520204 hasConcept C86803240 @default.
- W4231520204 hasConceptScore W4231520204C170748874 @default.
- W4231520204 hasConceptScore W4231520204C2756471 @default.
- W4231520204 hasConceptScore W4231520204C54355233 @default.
- W4231520204 hasConceptScore W4231520204C552990157 @default.
- W4231520204 hasConceptScore W4231520204C70721500 @default.
- W4231520204 hasConceptScore W4231520204C73573662 @default.
- W4231520204 hasConceptScore W4231520204C82381507 @default.
- W4231520204 hasConceptScore W4231520204C86803240 @default.
- W4231520204 hasIssue "6" @default.
- W4231520204 hasLocation W42315202041 @default.
- W4231520204 hasOpenAccess W4231520204 @default.
- W4231520204 hasPrimaryLocation W42315202041 @default.
- W4231520204 hasRelatedWork W1966154919 @default.
- W4231520204 hasRelatedWork W2000232541 @default.
- W4231520204 hasRelatedWork W2016016179 @default.
- W4231520204 hasRelatedWork W2026083933 @default.
- W4231520204 hasRelatedWork W2064036981 @default.
- W4231520204 hasRelatedWork W2112797008 @default.
- W4231520204 hasRelatedWork W2116083565 @default.
- W4231520204 hasRelatedWork W2119710453 @default.
- W4231520204 hasRelatedWork W2399813022 @default.
- W4231520204 hasRelatedWork W4308198592 @default.
- W4231520204 hasVolume "12" @default.
- W4231520204 isParatext "false" @default.
- W4231520204 isRetracted "false" @default.
- W4231520204 workType "article" @default.