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- W4231520244 abstract "A series of novel orally bioavailable small-molecule GPR119 agonists with improved potency and moderate physiochemical characteristics were designed, synthesized, and biologically evaluated. Among them, the most promising compound II-18 showed an EC50 value of 69 nM in in vitro cAMP assays and effectively lowered blood glucose excursions assessed by oral glucose tolerance test of normal mice." @default.
- W4231520244 created "2022-05-12" @default.
- W4231520244 date "2019-04-01" @default.
- W4231520244 modified "2023-10-16" @default.
- W4231520244 doi "https://doi.org/10.1002/ardp.v352.4" @default.
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