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- W4231551113 abstract "<h3>To the Editor.—</h3> Mucous membranes and systemic manifestations of toxic epidermal necrolysis (TEN) (also known as Lyell's syndrome) include oropharyngeal, ocular, genital, pulmonary, and intestinal involvement.<sup>1,2</sup>Hyperamylasemia was reported in only a few cases and its origin, ie, salivary and/or pancreatic, remained controversial.<sup>3,4</sup>The purpose of this study was to investigate the incidence and the origin of hyperamylasemia in TEN. <h3>Materials and Methods.—</h3> We reviewed retrospectively cases from 1985 through 1990 that fulfilled the criteria of TEN.<sup>1</sup>Sixty-four patients with at least two determinations of amylase were included in the study. Amylase was assayed using the colorimetric method (α-amylase, Merck-Clevenot, Chelles, France) (normal, 50 to 220 U/L). Patients with hyperamylasemia (at least twice normal) were age and sex matched with patients without hyperamylasemia. These two groups of patients with TEN were compared for involvement of body surface area and mucous membranes, biological parameters (glycemia, serum aminotransferases levels," @default.
- W4231551113 created "2022-05-12" @default.
- W4231551113 creator A5089131717 @default.
- W4231551113 date "1993-06-01" @default.
- W4231551113 modified "2023-10-16" @default.
- W4231551113 title "Hyperamylasemia in toxic epidermal necrolysis" @default.
- W4231551113 doi "https://doi.org/10.1001/archderm.129.6.792" @default.
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