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- W4231660614 abstract "WISE et al<sup>1</sup>first explored the realm of cutaneous immunofluorescence in 1962. After these initial steps, the landmark work of Beutner and Jordon<sup>2</sup>in the early '60s rapidly moved forward the diagnostic utility of cutaneous immunofluorescence and advanced our knowledge of the various vesiculobullous skin diseases, in which immunoreactants are demonstrated and thought to play a significant role. Even more sophisticated techniques have been developed that now provide remarkable insight into the anatomy of the dermal-epidermal structures and their interface and also provide insight into pathogenesis of these diseases and therapeutic potential for them. Since the last review of this situation in 1982, many advances have occurred in our understanding of the dermal-epidermal interface and pathophysiology of the mechanobullous or vesiculobullous diseases. This section updates our understanding of diseases previously covered (pemphigus, pemphigoid, dermatitis herpetiformis, chronic bullous dermatosis of childhood, and herpes gestationis) and adds an overview of" @default.
- W4231660614 created "2022-05-12" @default.
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- W4231660614 date "1987-11-27" @default.
- W4231660614 modified "2023-09-27" @default.
- W4231660614 title "Vesiculobullous skin disease with prominent immunologic feature" @default.
- W4231660614 doi "https://doi.org/10.1001/jama.258.20.2910" @default.
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