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• W423173634 abstract "Transdermal transport is now becoming one of the most convenient and safe pathways for drug delivery. In some cases it is necessary to use skin penetration enhancers in order to allow for the transdermal transport of drugs that are otherwise insufficiently skin-permeable. A series of oleanolic acid amides as potential transdermal penetration enhancers was formed by multistep synthesis and the synthesis of all newly prepared compounds is presented. The synthetized amides of oleanolic acid were tested for their in vitro penetration promoter activity. The above activity was evaluated by means of using the Fürst method. The relationships between the chemical structure of the studied compounds and penetration activity are presented." @default.
• W423173634 created "2016-06-24" @default.
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• W423173634 date "2015-05-26" @default.
• W423173634 modified "2023-10-18" @default.
• W423173634 title "Simple Amides of Oleanolic Acid as Effective Penetration Enhancers" @default.
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• W423173634 doi "https://doi.org/10.1371/journal.pone.0122857" @default.
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