FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4231837762> ?p ?o ?g. }

• W4231837762 endingPage "271" @default.
• W4231837762 startingPage "266" @default.
• W4231837762 abstract "Tributyltin (TBT) compounds have been widely used as antifouling agents for shipbottom paint. The immune system is a target of TBT intoxication. We evaluated the effects of TBT chloride in macrophages, which have critical roles in the immune system, using a murine macrophage lineage cell line, J774.1,in vitro. We examined tumor necrosis factor α (TNFα), interleukin-1β (IL-1β) andc-jun mRNA expression in J774.1 cells. The effects of TBT on the apoptosis of J774.1 cells were examined by determining the percentage of TUNEL-positive cells and caspase-3 activity. The mean values of the viabilities of J774.1 cells exposed to TBT decreased dose-dependently. The relative mRNA expression of TNFα increased dose-dependently, however, that of IL-1β was not significantly different among the groups. The mean percentage of TUNEL-positive cells increased dose-dependently. Increases in the caspase-3 activities of J774.1 cells were observed in the groups exposed to higher concentrations of TBT. The mean value of relative mRNA expression of c-Jun transcription factor increased dose-dependently. The increases in the percentage of TUNEL-positive cells and in caspase-3 activity suggested that exposure to TBT induces apoptosis of J774.1 cells. The increases in the mRNA expression of TNFα andc-jun by TBT may be related to apoptosis in macrophages." @default.
• W4231837762 created "2022-05-12" @default.
• W4231837762 creator A5044196816 @default.
• W4231837762 creator A5059980450 @default.
• W4231837762 creator A5086375855 @default.
• W4231837762 date "2004-01-01" @default.
• W4231837762 modified "2023-09-27" @default.
• W4231837762 title "Tributyltin (TBT) Increases TNF α mRNA Expression and Induces Apoptosis in the Murine Macrophage Cell Line in Vitro" @default.
• W4231837762 cites W1973328976 @default.
• W4231837762 cites W1975601462 @default.
• W4231837762 cites W1979515338 @default.
• W4231837762 cites W1980849207 @default.
• W4231837762 cites W1981300070 @default.
• W4231837762 cites W1988951544 @default.
• W4231837762 cites W1990342316 @default.
• W4231837762 cites W1994956146 @default.
• W4231837762 cites W1999269297 @default.
• W4231837762 cites W2002408632 @default.
• W4231837762 cites W2030252781 @default.
• W4231837762 cites W2034171588 @default.
• W4231837762 cites W2041750631 @default.
• W4231837762 cites W2042735198 @default.
• W4231837762 cites W2043830157 @default.
• W4231837762 cites W2049721676 @default.
• W4231837762 cites W2052980405 @default.
• W4231837762 cites W2078741480 @default.
• W4231837762 cites W2079338003 @default.
• W4231837762 cites W2080294916 @default.
• W4231837762 cites W2080603531 @default.
• W4231837762 cites W2080811816 @default.
• W4231837762 cites W2081045438 @default.
• W4231837762 cites W2081521827 @default.
• W4231837762 cites W2081920736 @default.
• W4231837762 cites W2086380499 @default.
• W4231837762 cites W2089372467 @default.
• W4231837762 cites W2093392246 @default.
• W4231837762 cites W2107907376 @default.
• W4231837762 cites W2125784520 @default.
• W4231837762 cites W2128635872 @default.
• W4231837762 cites W2138302361 @default.
• W4231837762 cites W2151723746 @default.
• W4231837762 cites W2172109010 @default.
• W4231837762 doi "https://doi.org/10.1265/ehpm.9.266" @default.
• W4231837762 hasPublicationYear "2004" @default.
• W4231837762 type Work @default.
• W4231837762 citedByCount "0" @default.
• W4231837762 crossrefType "journal-article" @default.
• W4231837762 hasAuthorship W4231837762A5044196816 @default.
• W4231837762 hasAuthorship W4231837762A5059980450 @default.
• W4231837762 hasAuthorship W4231837762A5086375855 @default.
• W4231837762 hasBestOaLocation W42318377621 @default.
• W4231837762 hasConcept C126322002 @default.
• W4231837762 hasConcept C134018914 @default.
• W4231837762 hasConcept C153911025 @default.
• W4231837762 hasConcept C16685009 @default.
• W4231837762 hasConcept C17991360 @default.
• W4231837762 hasConcept C185592680 @default.
• W4231837762 hasConcept C18903297 @default.
• W4231837762 hasConcept C190283241 @default.
• W4231837762 hasConcept C196795494 @default.
• W4231837762 hasConcept C202751555 @default.
• W4231837762 hasConcept C203014093 @default.
• W4231837762 hasConcept C2779078112 @default.
• W4231837762 hasConcept C2779244956 @default.
• W4231837762 hasConcept C31573885 @default.
• W4231837762 hasConcept C54355233 @default.
• W4231837762 hasConcept C55493867 @default.
• W4231837762 hasConcept C71924100 @default.
• W4231837762 hasConcept C81885089 @default.
• W4231837762 hasConcept C86803240 @default.
• W4231837762 hasConcept C8891405 @default.
• W4231837762 hasConcept C95444343 @default.
• W4231837762 hasConceptScore W4231837762C126322002 @default.
• W4231837762 hasConceptScore W4231837762C134018914 @default.
• W4231837762 hasConceptScore W4231837762C153911025 @default.
• W4231837762 hasConceptScore W4231837762C16685009 @default.
• W4231837762 hasConceptScore W4231837762C17991360 @default.
• W4231837762 hasConceptScore W4231837762C185592680 @default.
• W4231837762 hasConceptScore W4231837762C18903297 @default.
• W4231837762 hasConceptScore W4231837762C190283241 @default.
• W4231837762 hasConceptScore W4231837762C196795494 @default.
• W4231837762 hasConceptScore W4231837762C202751555 @default.
• W4231837762 hasConceptScore W4231837762C203014093 @default.
• W4231837762 hasConceptScore W4231837762C2779078112 @default.
• W4231837762 hasConceptScore W4231837762C2779244956 @default.
• W4231837762 hasConceptScore W4231837762C31573885 @default.
• W4231837762 hasConceptScore W4231837762C54355233 @default.
• W4231837762 hasConceptScore W4231837762C55493867 @default.
• W4231837762 hasConceptScore W4231837762C71924100 @default.
• W4231837762 hasConceptScore W4231837762C81885089 @default.
• W4231837762 hasConceptScore W4231837762C86803240 @default.
• W4231837762 hasConceptScore W4231837762C8891405 @default.
• W4231837762 hasConceptScore W4231837762C95444343 @default.
• W4231837762 hasIssue "6" @default.
• W4231837762 hasLocation W42318377621 @default.
• W4231837762 hasOpenAccess W4231837762 @default.
• W4231837762 hasPrimaryLocation W42318377621 @default.
• W4231837762 hasRelatedWork W1500853876 @default.

• next