Matches in SemOpenAlex for { <https://semopenalex.org/work/W4231990280> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4231990280 endingPage "895" @default.
- W4231990280 startingPage "889" @default.
- W4231990280 abstract "Ethylene glycols have been found to allow activation of purified preparations of human plasminogen. The activity of the enzyme formed, plasmin, was measured using TAMe (p-toluene-sulphonyl-L-arginine methyl ester) as a substrate. In 50% (v/v) solutions of these compounds at pH 7.6 and 30 °C, plasmin accumulated faster in diethylene and triethylene glycols than in glycerol, but in ethylene glycol no plasmin was found. When lower concentrations of ethylene glycol (from zero to 50%) and shorter times of incubation were used, plasmin was found. With equimolar solutions (4.3 M) of glycerol and the three glycols, only diethylene glycol showed a fast rate of accumulation of plasmin. A 50% triethylene glycol solution partially inhibited the rate of spontaneous activation but stabilized the plasmin formed and therefore enzyme accumulated. At room temperature more plasmin accumulated than at higher temperatures when plasminogen was incubated in 50% triethylene glycol solution, and no plasmin was found when plasminogen was incubated at pH 7.6, 30 °C, in 50% solutions of propylene glycols, several ethers of the ethylene glycols, several polymers of various glycols, and dioxane." @default.
- W4231990280 created "2022-05-12" @default.
- W4231990280 creator A5021807457 @default.
- W4231990280 date "1963-01-01" @default.
- W4231990280 modified "2023-09-29" @default.
- W4231990280 title "THE ACTIVATION OF PURIFIED HUMAN PLASMINOGEN IN SOLUTIONS OF ETHYLENE GLYCOLS" @default.
- W4231990280 cites W134566939 @default.
- W4231990280 cites W2325315926 @default.
- W4231990280 cites W2330481666 @default.
- W4231990280 cites W2335434134 @default.
- W4231990280 cites W2410028354 @default.
- W4231990280 cites W4241599334 @default.
- W4231990280 cites W78896514 @default.
- W4231990280 doi "https://doi.org/10.1139/y63-101" @default.
- W4231990280 hasPublicationYear "1963" @default.
- W4231990280 type Work @default.
- W4231990280 citedByCount "1" @default.
- W4231990280 crossrefType "journal-article" @default.
- W4231990280 hasAuthorship W4231990280A5021807457 @default.
- W4231990280 hasConcept C161790260 @default.
- W4231990280 hasConcept C178790620 @default.
- W4231990280 hasConcept C181199279 @default.
- W4231990280 hasConcept C185592680 @default.
- W4231990280 hasConcept C188027245 @default.
- W4231990280 hasConcept C2775934670 @default.
- W4231990280 hasConcept C2777516009 @default.
- W4231990280 hasConcept C2778597550 @default.
- W4231990280 hasConcept C2779136216 @default.
- W4231990280 hasConcept C2780881558 @default.
- W4231990280 hasConcept C2781071845 @default.
- W4231990280 hasConcept C43617362 @default.
- W4231990280 hasConceptScore W4231990280C161790260 @default.
- W4231990280 hasConceptScore W4231990280C178790620 @default.
- W4231990280 hasConceptScore W4231990280C181199279 @default.
- W4231990280 hasConceptScore W4231990280C185592680 @default.
- W4231990280 hasConceptScore W4231990280C188027245 @default.
- W4231990280 hasConceptScore W4231990280C2775934670 @default.
- W4231990280 hasConceptScore W4231990280C2777516009 @default.
- W4231990280 hasConceptScore W4231990280C2778597550 @default.
- W4231990280 hasConceptScore W4231990280C2779136216 @default.
- W4231990280 hasConceptScore W4231990280C2780881558 @default.
- W4231990280 hasConceptScore W4231990280C2781071845 @default.
- W4231990280 hasConceptScore W4231990280C43617362 @default.
- W4231990280 hasIssue "1" @default.
- W4231990280 hasLocation W42319902801 @default.
- W4231990280 hasOpenAccess W4231990280 @default.
- W4231990280 hasPrimaryLocation W42319902801 @default.
- W4231990280 hasRelatedWork W14950234 @default.
- W4231990280 hasRelatedWork W19003978 @default.
- W4231990280 hasRelatedWork W219591 @default.
- W4231990280 hasRelatedWork W24911590 @default.
- W4231990280 hasRelatedWork W25445107 @default.
- W4231990280 hasRelatedWork W29116553 @default.
- W4231990280 hasRelatedWork W29505315 @default.
- W4231990280 hasRelatedWork W30301974 @default.
- W4231990280 hasRelatedWork W8018719 @default.
- W4231990280 hasRelatedWork W16833309 @default.
- W4231990280 hasVolume "41" @default.
- W4231990280 isParatext "false" @default.
- W4231990280 isRetracted "false" @default.
- W4231990280 workType "article" @default.