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- W4232131065 abstract "Researchers investigating toxic reactions that killed two patients in a trial of interleukin-12 earlier this year have reached a surprising conclusion: The drug is highly toxic if it is given in multiple high doses, but those effects can be avoided if the multiple doses are preceded by a single dose followed by a rest period. The initial dose apparently imprints a memory on the immune system, but the mechanism is unclear." @default.
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- W4232131065 date "1995-11-10" @default.
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- W4232131065 title "IL-12 Deaths: Explanation and a Puzzle" @default.
- W4232131065 doi "https://doi.org/10.1126/science.270.5238.908.a" @default.
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