Matches in SemOpenAlex for { <https://semopenalex.org/work/W4232292757> ?p ?o ?g. }
- W4232292757 endingPage "65" @default.
- W4232292757 startingPage "19" @default.
- W4232292757 abstract "Cephalotaxine (CET) is a parent polycyclic scaffold for the class of Cephalotaxus alkaloids. The ester derivatives of CET, i.e., harringtonine (2), isoharringtonine (3), homoharringtonine (4), and deoxyharringtonine (5) show important anticancer activity against different types of leukemia (Fig. 4). In 1963, Paudler and his coworker isolated it from Cephalotaxus drupacea and Cephalotaxus fortunei. Later on, the stereochemistry of CET was established by Powell et al. via X-ray crystallography. The natural product (CET) possesses unique structural framework that consists of pentacyclic ring system with three contiguous stereogenic centers. The presence of quaternary center next to nitrogen is one of the key synthetic challenges in the synthesis of this CET. The interesting structural features of natural product and prominent biological activities of its ester derivatives make it attractive synthetic target for chemists to develop novel synthetic strategies and efficient synthetic routes." @default.
- W4232292757 created "2022-05-12" @default.
- W4232292757 creator A5010965377 @default.
- W4232292757 creator A5087959158 @default.
- W4232292757 creator A5091775788 @default.
- W4232292757 date "2021-01-01" @default.
- W4232292757 modified "2023-10-16" @default.
- W4232292757 title "Cephalotaxine" @default.
- W4232292757 cites W1842578691 @default.
- W4232292757 cites W1963619806 @default.
- W4232292757 cites W1965904818 @default.
- W4232292757 cites W1969315407 @default.
- W4232292757 cites W1970181325 @default.
- W4232292757 cites W1974486126 @default.
- W4232292757 cites W1986993358 @default.
- W4232292757 cites W1992313083 @default.
- W4232292757 cites W1997552086 @default.
- W4232292757 cites W1998570013 @default.
- W4232292757 cites W2001433594 @default.
- W4232292757 cites W2011161238 @default.
- W4232292757 cites W2015579097 @default.
- W4232292757 cites W2016930259 @default.
- W4232292757 cites W2028428925 @default.
- W4232292757 cites W2036920720 @default.
- W4232292757 cites W2042755027 @default.
- W4232292757 cites W2055916245 @default.
- W4232292757 cites W2058452788 @default.
- W4232292757 cites W2062696449 @default.
- W4232292757 cites W2072850426 @default.
- W4232292757 cites W2074951840 @default.
- W4232292757 cites W2088757280 @default.
- W4232292757 cites W2088855488 @default.
- W4232292757 cites W2093015072 @default.
- W4232292757 cites W2095529883 @default.
- W4232292757 cites W2109328411 @default.
- W4232292757 cites W2134369393 @default.
- W4232292757 cites W2136600532 @default.
- W4232292757 cites W2157393978 @default.
- W4232292757 cites W2283712598 @default.
- W4232292757 cites W2318074530 @default.
- W4232292757 cites W2320208805 @default.
- W4232292757 cites W2328485327 @default.
- W4232292757 cites W2330174288 @default.
- W4232292757 cites W2332026895 @default.
- W4232292757 cites W2342000645 @default.
- W4232292757 cites W2615502676 @default.
- W4232292757 cites W2921670040 @default.
- W4232292757 cites W2948678201 @default.
- W4232292757 cites W2949731894 @default.
- W4232292757 cites W2950559534 @default.
- W4232292757 cites W2952396227 @default.
- W4232292757 cites W2952436780 @default.
- W4232292757 cites W2952959082 @default.
- W4232292757 cites W2953131442 @default.
- W4232292757 doi "https://doi.org/10.1016/b978-0-12-822262-1.00004-4" @default.
- W4232292757 hasPublicationYear "2021" @default.
- W4232292757 type Work @default.
- W4232292757 citedByCount "2" @default.
- W4232292757 countsByYear W42322927572021 @default.
- W4232292757 countsByYear W42322927572022 @default.
- W4232292757 crossrefType "book-chapter" @default.
- W4232292757 hasAuthorship W4232292757A5010965377 @default.
- W4232292757 hasAuthorship W4232292757A5087959158 @default.
- W4232292757 hasAuthorship W4232292757A5091775788 @default.
- W4232292757 hasConcept C134195300 @default.
- W4232292757 hasConcept C146686406 @default.
- W4232292757 hasConcept C161790260 @default.
- W4232292757 hasConcept C178790620 @default.
- W4232292757 hasConcept C185592680 @default.
- W4232292757 hasConcept C2778461978 @default.
- W4232292757 hasConcept C2779396153 @default.
- W4232292757 hasConcept C2780378348 @default.
- W4232292757 hasConcept C2910157418 @default.
- W4232292757 hasConcept C54355233 @default.
- W4232292757 hasConcept C71240020 @default.
- W4232292757 hasConcept C86803240 @default.
- W4232292757 hasConceptScore W4232292757C134195300 @default.
- W4232292757 hasConceptScore W4232292757C146686406 @default.
- W4232292757 hasConceptScore W4232292757C161790260 @default.
- W4232292757 hasConceptScore W4232292757C178790620 @default.
- W4232292757 hasConceptScore W4232292757C185592680 @default.
- W4232292757 hasConceptScore W4232292757C2778461978 @default.
- W4232292757 hasConceptScore W4232292757C2779396153 @default.
- W4232292757 hasConceptScore W4232292757C2780378348 @default.
- W4232292757 hasConceptScore W4232292757C2910157418 @default.
- W4232292757 hasConceptScore W4232292757C54355233 @default.
- W4232292757 hasConceptScore W4232292757C71240020 @default.
- W4232292757 hasConceptScore W4232292757C86803240 @default.
- W4232292757 hasLocation W42322927571 @default.
- W4232292757 hasOpenAccess W4232292757 @default.
- W4232292757 hasPrimaryLocation W42322927571 @default.
- W4232292757 hasRelatedWork W2105182094 @default.
- W4232292757 hasRelatedWork W2334674240 @default.
- W4232292757 hasRelatedWork W2909418605 @default.
- W4232292757 hasRelatedWork W2950738265 @default.
- W4232292757 hasRelatedWork W2982951483 @default.
- W4232292757 hasRelatedWork W4232292757 @default.
- W4232292757 hasRelatedWork W4243284839 @default.