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- W4232336057 abstract "BACKGROUND: Transmission of Entamoeba histolytica generally occurs by fecal excretion of cysts followed by oral ingestion of contaminated food or water. However, fecal-oral transmission may occur within households and long-term care institutions, and sexual transmission occurs among men who have sex with men. Epidemiologically linked clusters of E. histolytica infection are rare in industrialized countries. We report such a sexually linked cluster in Canada.METHODS: An index case involving a young female with an amebic liver abscess led to an epidemiological investigation of sexual contacts. Anti-amebic serological analysis, stool specimen examinations, and abdominal ultrasounds were done for the contacts. Enzyme-linked immunosorbent assay was done for stool antigen specific to E. histolytica. Genotyping and phylogenetic analysis was performed on 1 stool isolate.RESULTS: By tracing sexual contacts related to the index case, we uncovered a cluster of 7 cases of amebiasis (3 with liver abscesses). Oral-anal sex was common in the group; the 5 female individuals were bisexual (4) or homosexual (1). The outbreak strain was genotyped, and cluster analysis indicated that this virulent strain differed substantially from asymptomatic or diarrheal E. histolytica isolates.CONCLUSIONS: E. histolytica can be transmitted by heterosexual activity as well as male and female homosexual activity. Patients with amebiasis should be counselled about possible sexual transmission. PMID: 19580413" @default.
- W4232336057 created "2022-05-12" @default.
- W4232336057 creator A5001742842 @default.
- W4232336057 date "2009-09-05" @default.
- W4232336057 modified "2023-09-26" @default.
- W4232336057 title "Faculty Opinions recommendation of A possible cluster of sexually transmitted Entamoeba histolytica: genetic analysis of a highly virulent strain." @default.
- W4232336057 doi "https://doi.org/10.3410/f.1164627.626423" @default.
- W4232336057 hasPublicationYear "2009" @default.
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