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- W4232808905 abstract "Replikation, Fällung, Signalverstärkung: Die durch Polymerasen oder Reverse Transkriptasen induzierte Replikation von DNA und RNA an einem Messwandler (einer Elektrode oder einem piezoelektrischen Kristall) erlaubt eine hochempfindliche, spezifische Analyse viraler Genome. Biotin-Markierungen (B) an den Doppelsträngen dienen als Andockstellen für eine Avidin(A)-modifizierte Alkalische Phosphatase (AP). Die enzymatische Umsetzung eines Substrats (S) zum unlöslichen Produkt (P), das sich auf dem Messwandler (gelbe Oberfläche) niederschlägt, ermöglicht eine beträchtliche Signalverstärkung." @default.
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- W4232808905 date "2001-06-18" @default.
- W4232808905 modified "2023-09-26" @default.
- W4232808905 title "Electronic Transduction of Polymerase or Reverse Transcriptase Induced Replication Processes on Surfaces: Highly Sensitive and Specific Detection of Viral Genomes" @default.
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- W4232808905 doi "https://doi.org/10.1002/1521-3757(20010618)113:12<2321::aid-ange2321>3.0.co;2-r" @default.
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