Matches in SemOpenAlex for { <https://semopenalex.org/work/W4232891922> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4232891922 endingPage "279" @default.
- W4232891922 startingPage "268" @default.
- W4232891922 abstract "The fragile X mutation and fragile X syndrome are associated with hyperarousal, hyperactivity, aggression, and anxiety. These may be related to strong reactions to auditory, tactile, visual, and olfactory stimuli [Hagerman, 1996b; Hagerman and Cronister, 1996]. However, almost no data exist describing hyperarousal and sensory sensitivity in individuals with the fragile X mutation. This study establishes a reliable laboratory paradigm for examining reactions to sensory stimuli. We found the pattern of electrodermal responses (EDRs) to stimulation in one sensory modality predicted the pattern of EDRs in four other sensory systems. In addition, the EDR pattern of individuals with the fragile X mutation was related to their FMR-protein expression. Finally, EDRs in individuals with fragile X syndrome were significantly different from those of normal controls, demonstrating greater magnitude, more responses per stimulation, responses on a greater proportion of trials, and lower rates of habituation. The findings support the theory that individuals with fragile X syndrome have a physiologically based enhancement of reactions to sensations. Because electrodermal activity indexes sympathetic nervous system activity, the data suggest that the over-arousal to sensation may involve the sympathetic system. Am. J. Med. Genet. 83:268–279, 1999. © 1999 Wiley-Liss, Inc." @default.
- W4232891922 created "2022-05-12" @default.
- W4232891922 creator A5005027429 @default.
- W4232891922 creator A5025540884 @default.
- W4232891922 creator A5026318601 @default.
- W4232891922 creator A5027142432 @default.
- W4232891922 creator A5048466078 @default.
- W4232891922 creator A5052061124 @default.
- W4232891922 creator A5061206215 @default.
- W4232891922 creator A5068831433 @default.
- W4232891922 creator A5080670298 @default.
- W4232891922 creator A5081574269 @default.
- W4232891922 date "1999-04-02" @default.
- W4232891922 modified "2023-10-16" @default.
- W4232891922 title "Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: A preliminary report" @default.
- W4232891922 doi "https://doi.org/10.1002/(sici)1096-8628(19990402)83:4<268::aid-ajmg7>3.3.co;2-b" @default.
- W4232891922 hasPublicationYear "1999" @default.
- W4232891922 type Work @default.
- W4232891922 citedByCount "5" @default.
- W4232891922 countsByYear W42328919222019 @default.
- W4232891922 crossrefType "journal-article" @default.
- W4232891922 hasAuthorship W4232891922A5005027429 @default.
- W4232891922 hasAuthorship W4232891922A5025540884 @default.
- W4232891922 hasAuthorship W4232891922A5026318601 @default.
- W4232891922 hasAuthorship W4232891922A5027142432 @default.
- W4232891922 hasAuthorship W4232891922A5048466078 @default.
- W4232891922 hasAuthorship W4232891922A5052061124 @default.
- W4232891922 hasAuthorship W4232891922A5061206215 @default.
- W4232891922 hasAuthorship W4232891922A5068831433 @default.
- W4232891922 hasAuthorship W4232891922A5080670298 @default.
- W4232891922 hasAuthorship W4232891922A5081574269 @default.
- W4232891922 hasConcept C118552586 @default.
- W4232891922 hasConcept C130093455 @default.
- W4232891922 hasConcept C138496976 @default.
- W4232891922 hasConcept C15744967 @default.
- W4232891922 hasConcept C169760540 @default.
- W4232891922 hasConcept C24998067 @default.
- W4232891922 hasConcept C25457674 @default.
- W4232891922 hasConcept C26486553 @default.
- W4232891922 hasConcept C2777630245 @default.
- W4232891922 hasConcept C36951298 @default.
- W4232891922 hasConcept C50610925 @default.
- W4232891922 hasConcept C548259974 @default.
- W4232891922 hasConcept C558461103 @default.
- W4232891922 hasConcept C71924100 @default.
- W4232891922 hasConcept C94487597 @default.
- W4232891922 hasConceptScore W4232891922C118552586 @default.
- W4232891922 hasConceptScore W4232891922C130093455 @default.
- W4232891922 hasConceptScore W4232891922C138496976 @default.
- W4232891922 hasConceptScore W4232891922C15744967 @default.
- W4232891922 hasConceptScore W4232891922C169760540 @default.
- W4232891922 hasConceptScore W4232891922C24998067 @default.
- W4232891922 hasConceptScore W4232891922C25457674 @default.
- W4232891922 hasConceptScore W4232891922C26486553 @default.
- W4232891922 hasConceptScore W4232891922C2777630245 @default.
- W4232891922 hasConceptScore W4232891922C36951298 @default.
- W4232891922 hasConceptScore W4232891922C50610925 @default.
- W4232891922 hasConceptScore W4232891922C548259974 @default.
- W4232891922 hasConceptScore W4232891922C558461103 @default.
- W4232891922 hasConceptScore W4232891922C71924100 @default.
- W4232891922 hasConceptScore W4232891922C94487597 @default.
- W4232891922 hasIssue "4" @default.
- W4232891922 hasLocation W42328919221 @default.
- W4232891922 hasOpenAccess W4232891922 @default.
- W4232891922 hasPrimaryLocation W42328919221 @default.
- W4232891922 hasRelatedWork W1825369211 @default.
- W4232891922 hasRelatedWork W1995893239 @default.
- W4232891922 hasRelatedWork W2011823904 @default.
- W4232891922 hasRelatedWork W2041723692 @default.
- W4232891922 hasRelatedWork W2044080614 @default.
- W4232891922 hasRelatedWork W2107291133 @default.
- W4232891922 hasRelatedWork W2414288209 @default.
- W4232891922 hasRelatedWork W2419961823 @default.
- W4232891922 hasRelatedWork W4292332798 @default.
- W4232891922 hasRelatedWork W4300549411 @default.
- W4232891922 hasVolume "83" @default.
- W4232891922 isParatext "false" @default.
- W4232891922 isRetracted "false" @default.
- W4232891922 workType "article" @default.