Matches in SemOpenAlex for { <https://semopenalex.org/work/W4233545813> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4233545813 endingPage "139" @default.
- W4233545813 startingPage "139" @default.
- W4233545813 abstract "The 90 kDa heat shock protein (Hsp90) induces the condensation of the chromatin structure [Csermely, P., Kajtár, J., Hollósi, M., Oikarinen, J., and Somogyi, J. (1994) Biochem. Biophys. Res. Commun. 202, 1657–1663]. In our present studies we used surface plasmon resonance measurements to demonstrate that Hsp90 binds histones H1, H2A, H2B, H3 and H4 with high affinity having dissociation constants in the submicromolar range. Strong binding of the C-terminal peptide of histone H1 containing the SPKK-motif and a pentaeicosa-peptide including the Hsp90 bipartite nuclear localization signal sequence was also observed. However, a lysine/argininerich peptide of casein, and the lysine-rich platelet factor 4 did not display a significant interaction with Hsp90. Histones and positively charged peptides modulated the Hsp90-associated kinase activity. Interactions between Hsp90, histones, and high mobility group (HMG) protein-derived peptides raise the possibility of the involvement of Hsp90 in chromatin reorganization during steroid action, mitosis, or after cellular stress." @default.
- W4233545813 created "2022-05-12" @default.
- W4233545813 date "1995-04-01" @default.
- W4233545813 modified "2023-09-26" @default.
- W4233545813 title "Fibre enriched in aglucone isoflavone" @default.
- W4233545813 doi "https://doi.org/10.1016/s0924-2244(00)89007-x" @default.
- W4233545813 hasPublicationYear "1995" @default.
- W4233545813 type Work @default.
- W4233545813 citedByCount "0" @default.
- W4233545813 crossrefType "journal-article" @default.
- W4233545813 hasConcept C101152365 @default.
- W4233545813 hasConcept C104317684 @default.
- W4233545813 hasConcept C12554922 @default.
- W4233545813 hasConcept C185592680 @default.
- W4233545813 hasConcept C205260736 @default.
- W4233545813 hasConcept C2775932338 @default.
- W4233545813 hasConcept C2776016237 @default.
- W4233545813 hasConcept C2776745794 @default.
- W4233545813 hasConcept C2779281246 @default.
- W4233545813 hasConcept C515207424 @default.
- W4233545813 hasConcept C552990157 @default.
- W4233545813 hasConcept C55493867 @default.
- W4233545813 hasConcept C64927066 @default.
- W4233545813 hasConcept C83640560 @default.
- W4233545813 hasConcept C86803240 @default.
- W4233545813 hasConceptScore W4233545813C101152365 @default.
- W4233545813 hasConceptScore W4233545813C104317684 @default.
- W4233545813 hasConceptScore W4233545813C12554922 @default.
- W4233545813 hasConceptScore W4233545813C185592680 @default.
- W4233545813 hasConceptScore W4233545813C205260736 @default.
- W4233545813 hasConceptScore W4233545813C2775932338 @default.
- W4233545813 hasConceptScore W4233545813C2776016237 @default.
- W4233545813 hasConceptScore W4233545813C2776745794 @default.
- W4233545813 hasConceptScore W4233545813C2779281246 @default.
- W4233545813 hasConceptScore W4233545813C515207424 @default.
- W4233545813 hasConceptScore W4233545813C552990157 @default.
- W4233545813 hasConceptScore W4233545813C55493867 @default.
- W4233545813 hasConceptScore W4233545813C64927066 @default.
- W4233545813 hasConceptScore W4233545813C83640560 @default.
- W4233545813 hasConceptScore W4233545813C86803240 @default.
- W4233545813 hasIssue "4" @default.
- W4233545813 hasLocation W42335458131 @default.
- W4233545813 hasOpenAccess W4233545813 @default.
- W4233545813 hasPrimaryLocation W42335458131 @default.
- W4233545813 hasRelatedWork W1509400502 @default.
- W4233545813 hasRelatedWork W1604628826 @default.
- W4233545813 hasRelatedWork W1965672865 @default.
- W4233545813 hasRelatedWork W1986231947 @default.
- W4233545813 hasRelatedWork W2008143037 @default.
- W4233545813 hasRelatedWork W2019555328 @default.
- W4233545813 hasRelatedWork W2059345652 @default.
- W4233545813 hasRelatedWork W2066899538 @default.
- W4233545813 hasRelatedWork W2203073619 @default.
- W4233545813 hasRelatedWork W2434482954 @default.
- W4233545813 hasVolume "6" @default.
- W4233545813 isParatext "false" @default.
- W4233545813 isRetracted "false" @default.
- W4233545813 workType "article" @default.