FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4233650693> ?p ?o ?g. }

• W4233650693 endingPage "711" @default.
• W4233650693 startingPage "710" @default.
• W4233650693 abstract "This article [1Koshida Y. Watanabe G. Yasuda T. Tomita S. Kadoya S. Kanamori T. Portable coronary active perfusion system for off-pump coronary artery bypass grafting.Ann Thorac Surg. 2006; 81: 706-711Abstract Full Text Full Text PDF PubMed Scopus (6) Google Scholar] describes a novel active coronary perfusion system for use in off-pump coronary artery bypass (OPCAB) procedures. The authors tested this system in normal in-situ porcine hearts. They demonstrated stable electrophysiologic and contractile function for 30 minutes in myocardium perfused by their pump, and there was no evidence of acute vascular injury from the intracoronary cannula.Other investigators have shown the potential for active coronary perfusion systems to diminish ischemic injury during OPCAB procedures. The advantage of the system described in this report is its simplicity and small size. There is no need for personnel dedicated only to running the pump. Presumably drugs (eg, nitroglycerine or adenosine) can be added to the blood perfusing the coronary artery. The limitations of this approach are as follows: first, the need for active perfusion devices and the indications for their use are not clearly defined. Should all OPCAB patients have active perfusion, or just specific subgroups? Second, this pump delivers a constant flow but does not monitor or modulate coronary pressure. If there is small vessel disease or atherosclerosis distal to the cannulation site, resistance to flow will be higher than usual with consequent high intracoronary pressures that may cause myocardial edema. The authors believe that high intracoronary pressure will increase backflow around the cannula, but this pop-off mechanism is imprecise. Third, the maximum flow of the pump (100 mL/min) may not be sufficient for feeding multiple grafts.Clinical data are needed to determine the usefulness and indications for this device in OPCAB surgery. Simplicity and low cost are important advantages in the operating room that will give this concept an edge over more complex systems if the aforementioned limitations can be minimized by design modifications. This article [1Koshida Y. Watanabe G. Yasuda T. Tomita S. Kadoya S. Kanamori T. Portable coronary active perfusion system for off-pump coronary artery bypass grafting.Ann Thorac Surg. 2006; 81: 706-711Abstract Full Text Full Text PDF PubMed Scopus (6) Google Scholar] describes a novel active coronary perfusion system for use in off-pump coronary artery bypass (OPCAB) procedures. The authors tested this system in normal in-situ porcine hearts. They demonstrated stable electrophysiologic and contractile function for 30 minutes in myocardium perfused by their pump, and there was no evidence of acute vascular injury from the intracoronary cannula. Other investigators have shown the potential for active coronary perfusion systems to diminish ischemic injury during OPCAB procedures. The advantage of the system described in this report is its simplicity and small size. There is no need for personnel dedicated only to running the pump. Presumably drugs (eg, nitroglycerine or adenosine) can be added to the blood perfusing the coronary artery. The limitations of this approach are as follows: first, the need for active perfusion devices and the indications for their use are not clearly defined. Should all OPCAB patients have active perfusion, or just specific subgroups? Second, this pump delivers a constant flow but does not monitor or modulate coronary pressure. If there is small vessel disease or atherosclerosis distal to the cannulation site, resistance to flow will be higher than usual with consequent high intracoronary pressures that may cause myocardial edema. The authors believe that high intracoronary pressure will increase backflow around the cannula, but this pop-off mechanism is imprecise. Third, the maximum flow of the pump (100 mL/min) may not be sufficient for feeding multiple grafts. Clinical data are needed to determine the usefulness and indications for this device in OPCAB surgery. Simplicity and low cost are important advantages in the operating room that will give this concept an edge over more complex systems if the aforementioned limitations can be minimized by design modifications." @default.
• W4233650693 created "2022-05-12" @default.
• W4233650693 creator A5065926161 @default.
• W4233650693 date "2006-02-01" @default.
• W4233650693 modified "2023-09-30" @default.
• W4233650693 title "Invited commentary" @default.
• W4233650693 doi "https://doi.org/10.1016/j.athoracsur.2005.07.093" @default.
• W4233650693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16427879" @default.
• W4233650693 hasPublicationYear "2006" @default.
• W4233650693 type Work @default.
• W4233650693 citedByCount "0" @default.
• W4233650693 crossrefType "journal-article" @default.
• W4233650693 hasAuthorship W4233650693A5065926161 @default.
• W4233650693 hasConcept C126322002 @default.
• W4233650693 hasConcept C141071460 @default.
• W4233650693 hasConcept C146957229 @default.
• W4233650693 hasConcept C158846371 @default.
• W4233650693 hasConcept C164705383 @default.
• W4233650693 hasConcept C2776157398 @default.
• W4233650693 hasConcept C2776820930 @default.
• W4233650693 hasConcept C2778074680 @default.
• W4233650693 hasConcept C2778213512 @default.
• W4233650693 hasConcept C2780069944 @default.
• W4233650693 hasConcept C3017915907 @default.
• W4233650693 hasConcept C71924100 @default.
• W4233650693 hasConceptScore W4233650693C126322002 @default.
• W4233650693 hasConceptScore W4233650693C141071460 @default.
• W4233650693 hasConceptScore W4233650693C146957229 @default.
• W4233650693 hasConceptScore W4233650693C158846371 @default.
• W4233650693 hasConceptScore W4233650693C164705383 @default.
• W4233650693 hasConceptScore W4233650693C2776157398 @default.
• W4233650693 hasConceptScore W4233650693C2776820930 @default.
• W4233650693 hasConceptScore W4233650693C2778074680 @default.
• W4233650693 hasConceptScore W4233650693C2778213512 @default.
• W4233650693 hasConceptScore W4233650693C2780069944 @default.
• W4233650693 hasConceptScore W4233650693C3017915907 @default.
• W4233650693 hasConceptScore W4233650693C71924100 @default.
• W4233650693 hasIssue "2" @default.
• W4233650693 hasLocation W42336506931 @default.
• W4233650693 hasLocation W42336506932 @default.
• W4233650693 hasOpenAccess W4233650693 @default.
• W4233650693 hasPrimaryLocation W42336506931 @default.
• W4233650693 hasRelatedWork W1986318255 @default.
• W4233650693 hasRelatedWork W2009729242 @default.
• W4233650693 hasRelatedWork W2037192659 @default.
• W4233650693 hasRelatedWork W2070543526 @default.
• W4233650693 hasRelatedWork W2070670909 @default.
• W4233650693 hasRelatedWork W2110800524 @default.
• W4233650693 hasRelatedWork W2353302966 @default.
• W4233650693 hasRelatedWork W2412840556 @default.
• W4233650693 hasRelatedWork W2742597923 @default.
• W4233650693 hasRelatedWork W4321452690 @default.
• W4233650693 hasVolume "81" @default.
• W4233650693 isParatext "false" @default.
• W4233650693 isRetracted "false" @default.
• W4233650693 workType "article" @default.