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• W4233670016 abstract "To systematize information about vitamin E concentration in human milk and the variables associated with this composition in order to find possible causes of deficiency, supporting strategies to prevent it in postpartum women and infants. Studies published between 2004 and 2014 that assayed alpha‐tocopherol in human milk of healthy women by high performance liquid chromatography were evaluated. The keywords used were “vitamin E”, “alpha‐tocopherol”, “milk, human”, “lactation”, “infant, newborn” equivalents in Portuguese, in the BIREME, CAPES, PubMed, SciELO, ISI Web of Knowledge, HighWire Press, Ingenta, and Brazilian Digital Library of Theses and Dissertations databases. Of the 41 publications found on the subject, 25 articles whose full text was available and met the inclusion criteria were selected. The alpha‐tocopherol concentrations found in milk were similar in most populations studied. The variable phase of lactation was shown to influence vitamin E content in milk, which is reduced until the mature milk appears. Maternal variables parity, anthropometric nutritional status, socioeconomic status, and habitual dietary intake did not appear to affect the alpha‐tocopherol levels in milk. However, the influence of the variables maternal age, gestational age, biochemical nutritional status in alpha‐tocopherol, and maternal supplementation with vitamin E had conflicting results in the literature. Alpha‐tocopherol concentration in milk decreases during lactation, until the mature milk appears. To confirm the influence of some maternal and child variables on milk vitamin E content, further studies with adequate design are needed. Sistematizar informações sobre a concentração de vitamina E no leite humano e variáveis associadas a essa composição, a fim de encontrar possíveis causas de deficiência, subsidiando estratégias para prevenção desta em puérperas e lactentes. Foram avaliados estudos publicados entre 2004 e 2014 que determinaram o alfa‐tocoferol no leite humano de mulheres saudáveis por Cromatografia Líquida de Alta Eficiência. Os descritores utilizados foram “leite humano”, “alfa‐tocoferol”, “vitamina E”, “lactação” e seus equivalentes em inglês, nas bases de dados BIREME, Periódicos CAPES, PubMed, SciELO, ISI Web of Knowledge, HighWire Press, Ingenta e Biblioteca Digital Brasileira de Teses e Dissertações. Das 41 publicações encontradas sobre a temática, 25 foram selecionadas, por possuirem texto completo disponível e se encaixarem nos critérios de inclusão. As concentrações encontradas de alfa‐tocoferol no leite foram semelhantes na maioria das populações estudadas. A variável fase de lactação mostrou influenciar o conteúdo dessa vitamina no leite, que vai sendo reduzido até o leite maduro. As variáveis maternas paridade, estado nutricional antropométrico, condição socioeconômica e ingestão dietética habitual parecem não afetar os níveis de alfa‐tocoferol no leite. Entretanto, a influência das variáveis idade materna, idade gestacional, estado nutricional bioquímico em alfa‐tocoferol e suplementação materna com vitamina E possui resultados conflitantes na literatura. A concentração de alfa‐tocoferol no leite diminui durante a lactação, até chegar ao leite maduro. Para confirmar a influência de algumas variáveis maternas e da criança sobre a vitamina E do leite ainda são necessários mais estudos, com desenho adequado." @default.
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• W4233670016 date "2014-09-01" @default.
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• W4233670016 title "Vitamin E concentration in human milk and associated factors: a literature review" @default.
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