Matches in SemOpenAlex for { <https://semopenalex.org/work/W4233701741> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W4233701741 endingPage "1797" @default.
- W4233701741 startingPage "1797" @default.
- W4233701741 abstract "Purpose: To evaluate the protective and restoring effects of allicin in 7,12-dimethylbenz(a)anthracene (DMBA)-induced buccal pouch carcinogenesis.Methods: 1 week after receiving allicin (20 mg/kg body weight) orally, the buccal pouches of hamsters were painted daily with 0.5% 7,12-dimethylbenz(a)anthracene (DMBA) in liquid paraffin for 14 weeks and then every other day for another 2 weeks, after receiving allicin orally and thereafter for 14 weeks. The protective effects of allicin was evaluated by measuring the tumour incidence, tumour volume and tumour burdens as well as the levels of glycoconjugates were analyzed by using specific colorimetric methods. Animals not exposed to allicin and/or DMBA, those exposed to DMBA alone and others exposed to allicin alone served as controls.Results: Allicin significantly reduced the tumour incidence, tumour volume and tumour burden. DMBAaltered glycoconjugates in plasma, buccal mucosa tumour tissues and erythrocyte membrane of tumour bearing hamsters were normalized after treated with allicin.Conclusion: The results suggest that allicin has considerable potential to protect and restore the cell surface glycoconjugates moieties in the presence of allicin or possibly other oral carcinogenic agents.Keywords: Oral cancer, 7,12-dimethylbenz(a)anthracene, cell surface glycoconjugates, allicin, diallyl thiosulfinate" @default.
- W4233701741 created "2022-05-12" @default.
- W4233701741 creator A5004759200 @default.
- W4233701741 date "2017-09-06" @default.
- W4233701741 modified "2023-09-27" @default.
- W4233701741 title "Protective role of allicin (diallyl thiosulfinate) on cell surface glycoconjugate moieties in 7,12-dimethylbenz(a) anthracene-induced oral carcinogenesis" @default.
- W4233701741 doi "https://doi.org/10.4314/tjpr.v16i8.7" @default.
- W4233701741 hasPublicationYear "2017" @default.
- W4233701741 type Work @default.
- W4233701741 citedByCount "8" @default.
- W4233701741 countsByYear W42337017412019 @default.
- W4233701741 countsByYear W42337017412022 @default.
- W4233701741 countsByYear W42337017412023 @default.
- W4233701741 crossrefType "journal-article" @default.
- W4233701741 hasAuthorship W4233701741A5004759200 @default.
- W4233701741 hasBestOaLocation W42337017411 @default.
- W4233701741 hasConcept C104317684 @default.
- W4233701741 hasConcept C114246631 @default.
- W4233701741 hasConcept C13426554 @default.
- W4233701741 hasConcept C178790620 @default.
- W4233701741 hasConcept C185592680 @default.
- W4233701741 hasConcept C2776260934 @default.
- W4233701741 hasConcept C2778938436 @default.
- W4233701741 hasConcept C2779563022 @default.
- W4233701741 hasConcept C2781005338 @default.
- W4233701741 hasConcept C55493867 @default.
- W4233701741 hasConcept C555283112 @default.
- W4233701741 hasConcept C71924100 @default.
- W4233701741 hasConcept C98274493 @default.
- W4233701741 hasConceptScore W4233701741C104317684 @default.
- W4233701741 hasConceptScore W4233701741C114246631 @default.
- W4233701741 hasConceptScore W4233701741C13426554 @default.
- W4233701741 hasConceptScore W4233701741C178790620 @default.
- W4233701741 hasConceptScore W4233701741C185592680 @default.
- W4233701741 hasConceptScore W4233701741C2776260934 @default.
- W4233701741 hasConceptScore W4233701741C2778938436 @default.
- W4233701741 hasConceptScore W4233701741C2779563022 @default.
- W4233701741 hasConceptScore W4233701741C2781005338 @default.
- W4233701741 hasConceptScore W4233701741C55493867 @default.
- W4233701741 hasConceptScore W4233701741C555283112 @default.
- W4233701741 hasConceptScore W4233701741C71924100 @default.
- W4233701741 hasConceptScore W4233701741C98274493 @default.
- W4233701741 hasIssue "8" @default.
- W4233701741 hasLocation W42337017411 @default.
- W4233701741 hasOpenAccess W4233701741 @default.
- W4233701741 hasPrimaryLocation W42337017411 @default.
- W4233701741 hasRelatedWork W1554537892 @default.
- W4233701741 hasRelatedWork W159472903 @default.
- W4233701741 hasRelatedWork W2085441875 @default.
- W4233701741 hasRelatedWork W2092703933 @default.
- W4233701741 hasRelatedWork W2168444622 @default.
- W4233701741 hasRelatedWork W2246519231 @default.
- W4233701741 hasRelatedWork W2414492442 @default.
- W4233701741 hasRelatedWork W2460918933 @default.
- W4233701741 hasRelatedWork W4233701741 @default.
- W4233701741 hasRelatedWork W628537020 @default.
- W4233701741 hasVolume "16" @default.
- W4233701741 isParatext "false" @default.
- W4233701741 isRetracted "false" @default.
- W4233701741 workType "article" @default.