Matches in SemOpenAlex for { <https://semopenalex.org/work/W4233761566> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4233761566 endingPage "392" @default.
- W4233761566 startingPage "388" @default.
- W4233761566 abstract "Inflammatory mediators such as tumor necrosis factor (TNF) and interleukin-1 enhance tumor colony formation in different models of experimental and spontaneous metastasis. The involvement of the natural killer (NK) cell system in this process was investigated. Tumor necrosis factor does not appear to act directly on tumor cells by reducing their susceptibility to the cytotoxic action of NK cells but rather impairs NK activity in tumor-bearing mice. Such impairment of the natural killer system might be one means by which TNF supports tumor colony formation. Even though the metastasis-enhancing effect of TNF remained detectable in mice which have a greatly reduced NK cell cytotoxic activity due to a defect in the bg locus, normal mice which were depleted of NK cells by antibody treatment did not show enhanced metastasis after TNF injection. Therefore, the TNF-enhanced metastasis can only be seen as long as some NK cell function is operating in the animals. © 1996 Wiley-Liss, Inc." @default.
- W4233761566 created "2022-05-12" @default.
- W4233761566 creator A5022175835 @default.
- W4233761566 creator A5074621493 @default.
- W4233761566 creator A5075822843 @default.
- W4233761566 creator A5088717535 @default.
- W4233761566 date "1996-05-03" @default.
- W4233761566 modified "2023-09-27" @default.
- W4233761566 title "TNF promotes metastasis by impairing natural killer cell activity" @default.
- W4233761566 doi "https://doi.org/10.1002/(sici)1097-0215(19960503)66:3<388::aid-ijc20>3.3.co;2-9" @default.
- W4233761566 hasPublicationYear "1996" @default.
- W4233761566 type Work @default.
- W4233761566 citedByCount "0" @default.
- W4233761566 crossrefType "journal-article" @default.
- W4233761566 hasAuthorship W4233761566A5022175835 @default.
- W4233761566 hasAuthorship W4233761566A5074621493 @default.
- W4233761566 hasAuthorship W4233761566A5075822843 @default.
- W4233761566 hasAuthorship W4233761566A5088717535 @default.
- W4233761566 hasBestOaLocation W42337615661 @default.
- W4233761566 hasConcept C121608353 @default.
- W4233761566 hasConcept C129374314 @default.
- W4233761566 hasConcept C154317977 @default.
- W4233761566 hasConcept C17991360 @default.
- W4233761566 hasConcept C202751555 @default.
- W4233761566 hasConcept C203014093 @default.
- W4233761566 hasConcept C2776090121 @default.
- W4233761566 hasConcept C2778102761 @default.
- W4233761566 hasConcept C2779013556 @default.
- W4233761566 hasConcept C28651165 @default.
- W4233761566 hasConcept C502942594 @default.
- W4233761566 hasConcept C54355233 @default.
- W4233761566 hasConcept C55493867 @default.
- W4233761566 hasConcept C86803240 @default.
- W4233761566 hasConcept C8891405 @default.
- W4233761566 hasConceptScore W4233761566C121608353 @default.
- W4233761566 hasConceptScore W4233761566C129374314 @default.
- W4233761566 hasConceptScore W4233761566C154317977 @default.
- W4233761566 hasConceptScore W4233761566C17991360 @default.
- W4233761566 hasConceptScore W4233761566C202751555 @default.
- W4233761566 hasConceptScore W4233761566C203014093 @default.
- W4233761566 hasConceptScore W4233761566C2776090121 @default.
- W4233761566 hasConceptScore W4233761566C2778102761 @default.
- W4233761566 hasConceptScore W4233761566C2779013556 @default.
- W4233761566 hasConceptScore W4233761566C28651165 @default.
- W4233761566 hasConceptScore W4233761566C502942594 @default.
- W4233761566 hasConceptScore W4233761566C54355233 @default.
- W4233761566 hasConceptScore W4233761566C55493867 @default.
- W4233761566 hasConceptScore W4233761566C86803240 @default.
- W4233761566 hasConceptScore W4233761566C8891405 @default.
- W4233761566 hasIssue "3" @default.
- W4233761566 hasLocation W42337615661 @default.
- W4233761566 hasOpenAccess W4233761566 @default.
- W4233761566 hasPrimaryLocation W42337615661 @default.
- W4233761566 hasRelatedWork W1483170373 @default.
- W4233761566 hasRelatedWork W1965995080 @default.
- W4233761566 hasRelatedWork W1976185334 @default.
- W4233761566 hasRelatedWork W1992654999 @default.
- W4233761566 hasRelatedWork W2027256771 @default.
- W4233761566 hasRelatedWork W2154561989 @default.
- W4233761566 hasRelatedWork W2162741311 @default.
- W4233761566 hasRelatedWork W2475299811 @default.
- W4233761566 hasRelatedWork W4233761566 @default.
- W4233761566 hasRelatedWork W1573582813 @default.
- W4233761566 hasVolume "66" @default.
- W4233761566 isParatext "false" @default.
- W4233761566 isRetracted "false" @default.
- W4233761566 workType "article" @default.