Matches in SemOpenAlex for { <https://semopenalex.org/work/W4234020912> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4234020912 abstract "Abstract Purpose The purpose of this study was to assess trends in incidence and presentation of colorectal cancer (CRC) over a period of 37 years in a stable population in Mid-Norway. Secondarily, we wanted to predict the future burden of CRC in the same catchment area. Methods All 2268 patients diagnosed with CRC at Levanger Hospital between 1980 and 2016 were included in this study. We used Poisson regression to calculate the incidence rate ratio (IRR) and analyse factors associated with incidence. Results The incidence of CRC increased from 43/100,000 person-years during 1980–1984 to 84/100,000 person-years during 2012–2016. Unadjusted IRR increased by 1.8% per year, corresponding to an overall increase in incidence of 94.5%. Changes in population (ageing and sex distribution) contributed to 28% of this increase, whereas 72% must be attributed to primary preventable factors associated with lifestyle. Compared with the last observational period, we predict a further 40% increase by 2030, and a 70% increase by 2040. Acute colorectal obstruction was associated with tumours in the left flexure and descending colon. Spontaneous colorectal perforation was associated with tumours in the descending colon, caecum, and sigmoid colon. The incidence of obstruction remained stable, while the incidence of perforation decreased throughout the observational period. The proportion of earlier stages at diagnosis increased significantly in recent decades. Conclusion CRC incidence increased substantially from 1980 to 2016, mainly due to primary preventable factors. The incidence will continue to increase during the next two decades, mainly due to further ageing of the population." @default.
- W4234020912 created "2022-05-12" @default.
- W4234020912 creator A5023548211 @default.
- W4234020912 creator A5032785967 @default.
- W4234020912 creator A5035946466 @default.
- W4234020912 creator A5041167227 @default.
- W4234020912 creator A5049669618 @default.
- W4234020912 date "2020-04-15" @default.
- W4234020912 modified "2023-10-10" @default.
- W4234020912 title "Long-term trends in colorectal cancer: incidence, localization, and presentation" @default.
- W4234020912 doi "https://doi.org/10.21203/rs.3.rs-22840/v1" @default.
- W4234020912 hasPublicationYear "2020" @default.
- W4234020912 type Work @default.
- W4234020912 citedByCount "1" @default.
- W4234020912 countsByYear W42340209122022 @default.
- W4234020912 crossrefType "posted-content" @default.
- W4234020912 hasAuthorship W4234020912A5023548211 @default.
- W4234020912 hasAuthorship W4234020912A5032785967 @default.
- W4234020912 hasAuthorship W4234020912A5035946466 @default.
- W4234020912 hasAuthorship W4234020912A5041167227 @default.
- W4234020912 hasAuthorship W4234020912A5049669618 @default.
- W4234020912 hasBestOaLocation W42340209121 @default.
- W4234020912 hasConcept C120665830 @default.
- W4234020912 hasConcept C121332964 @default.
- W4234020912 hasConcept C121608353 @default.
- W4234020912 hasConcept C126322002 @default.
- W4234020912 hasConcept C141071460 @default.
- W4234020912 hasConcept C144024400 @default.
- W4234020912 hasConcept C149923435 @default.
- W4234020912 hasConcept C191897082 @default.
- W4234020912 hasConcept C192562407 @default.
- W4234020912 hasConcept C23131810 @default.
- W4234020912 hasConcept C2776870353 @default.
- W4234020912 hasConcept C2778292851 @default.
- W4234020912 hasConcept C2778456384 @default.
- W4234020912 hasConcept C2778527123 @default.
- W4234020912 hasConcept C2781074409 @default.
- W4234020912 hasConcept C2908647359 @default.
- W4234020912 hasConcept C526805850 @default.
- W4234020912 hasConcept C61511704 @default.
- W4234020912 hasConcept C71924100 @default.
- W4234020912 hasConcept C73269764 @default.
- W4234020912 hasConcept C99454951 @default.
- W4234020912 hasConceptScore W4234020912C120665830 @default.
- W4234020912 hasConceptScore W4234020912C121332964 @default.
- W4234020912 hasConceptScore W4234020912C121608353 @default.
- W4234020912 hasConceptScore W4234020912C126322002 @default.
- W4234020912 hasConceptScore W4234020912C141071460 @default.
- W4234020912 hasConceptScore W4234020912C144024400 @default.
- W4234020912 hasConceptScore W4234020912C149923435 @default.
- W4234020912 hasConceptScore W4234020912C191897082 @default.
- W4234020912 hasConceptScore W4234020912C192562407 @default.
- W4234020912 hasConceptScore W4234020912C23131810 @default.
- W4234020912 hasConceptScore W4234020912C2776870353 @default.
- W4234020912 hasConceptScore W4234020912C2778292851 @default.
- W4234020912 hasConceptScore W4234020912C2778456384 @default.
- W4234020912 hasConceptScore W4234020912C2778527123 @default.
- W4234020912 hasConceptScore W4234020912C2781074409 @default.
- W4234020912 hasConceptScore W4234020912C2908647359 @default.
- W4234020912 hasConceptScore W4234020912C526805850 @default.
- W4234020912 hasConceptScore W4234020912C61511704 @default.
- W4234020912 hasConceptScore W4234020912C71924100 @default.
- W4234020912 hasConceptScore W4234020912C73269764 @default.
- W4234020912 hasConceptScore W4234020912C99454951 @default.
- W4234020912 hasLocation W42340209121 @default.
- W4234020912 hasLocation W42340209122 @default.
- W4234020912 hasLocation W42340209123 @default.
- W4234020912 hasOpenAccess W4234020912 @default.
- W4234020912 hasPrimaryLocation W42340209121 @default.
- W4234020912 hasRelatedWork W2163274728 @default.
- W4234020912 hasRelatedWork W2235371377 @default.
- W4234020912 hasRelatedWork W2376769477 @default.
- W4234020912 hasRelatedWork W2389680203 @default.
- W4234020912 hasRelatedWork W2911740078 @default.
- W4234020912 hasRelatedWork W3082153399 @default.
- W4234020912 hasRelatedWork W3098564960 @default.
- W4234020912 hasRelatedWork W4234020912 @default.
- W4234020912 hasRelatedWork W4251229491 @default.
- W4234020912 hasRelatedWork W4252804459 @default.
- W4234020912 isParatext "false" @default.
- W4234020912 isRetracted "false" @default.
- W4234020912 workType "article" @default.