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- W4234052011 abstract "The article from Topkara and colleagues [1Topkara V.K. O'Neill J.K. Carlisle A. Novak E. Silvestry S.C. Ewald G.A. HeartWare and HeartMate II left ventricular assist devices as bridge to transplantation: a comparative analysis.Ann Thorac Surg. 2014; 97: 506-513Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar] describes a retrospective nonrandomized analysis of 1824 patients with Thoratec HeartMate II (HMII) and 141 patients with HeartWare HVAD implantation. Data were collected from the Organ Procurement and Transplantation network databank. The article has not shown any significant differences in the outcomes after bridging to cardiac transplantation with the applied pump systems. As recently reported, the ADVANCE Trial proved the noninferiority of the HeartWare HVAD pump in a comparison with HMII LVAD in a bridge to cardiac transplant cohort of patients, which implies the clinical justification of this work. Limitations include the higher number of patients in the HM II group and the assumption that a higher proportion of this group of patients was treated for real-life indications, which are less restrictive than clinical trial inclusion criteria under which the HVAD group was enrolled. Additionally, the limited resource of the registry data bank does not allow for a more detailed analysis. The higher number of female patients, as well as the lower BSA in the HVAD group, are important findings reflecting selection bias by some groups. The potential benefits of these findings should be confirmed in future research. Aside from the noted limitations of the trial, this study provides a major platform for research, offering further clarification and comparative details. HeartWare and HeartMate II Left Ventricular Assist Devices as Bridge to Transplantation: A Comparative AnalysisThe Annals of Thoracic SurgeryVol. 97Issue 2PreviewThe purpose of this study is to comparatively analyze outcomes of heart transplant patients bridged to transplantation with HeartWare (HW-VAD) versus HeartMate II (HMII-VAD) left ventricular assist devices. Full-Text PDF" @default.
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- W4234052011 date "2014-02-01" @default.
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- W4234052011 title "Invited Commentary" @default.
- W4234052011 doi "https://doi.org/10.1016/j.athoracsur.2013.09.037" @default.
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