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- W4234076069 abstract "A specific radioimmunological method for measurement of immunoreactive calcitonin (iCT) in human serum and tissue is described. Of healthy individuals of both sexes, 85% had measurable iCT in serum (mean, 0.23 ng/ ml). Of 29 patients who had received treatment for medullary carcinoma of the thyroid gland (MCT), 19 had increased serum iCT (0.60 ng/ml to 205 ng/ ml). Elevated serum iCT was also found preoperatively in 2 MCT patients. Eleven of the patients with abnormal elevations of serum iCT were alive 4 to 13 years after the operation. Concentration of iCT in extracts from MCT varied from 0.5 to 540 ng/ml wet weight. The diagnostic value of this method and its importance for pre- and post-operative evaluation of these patients are improved by the use of selective venous catheterization in basal state and during stimulation of CT secretion." @default.
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- W4234076069 date "1976-07-01" @default.
- W4234076069 modified "2023-10-18" @default.
- W4234076069 title "Radioimmunoassay of Human Calcitonin in Serum and Tissue from Healthy Individuals and Patients with Medullary Carcinoma of the Thyroid Gland" @default.
- W4234076069 doi "https://doi.org/10.3109/00365517609055267" @default.
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