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- W4234104381 abstract "This chapter presents the comparative studies on the use of hypnosedatives and anxiolytics. The anxiolytic buspirone in therapeutic doses appears to have less detectable deleterious effects on cognition when given acutely. Intravenous sodium valproate has been compared with an infusion of diazepam for control of refractory status epilepticus in an open, randomized study in 40 children with refractory status epilepticus. It is found there were no adverse effects on liver function with valproate. High-dose of diazepam is found to be associated with time-dependent increases in the intensity of subjective drug effects (strength of drug effect, sedation) and reductions in psychological performance in patients taking methadone or buprenorphine. While studying the effects of lorazepam on psychology, it is found that Acute lorazepam affected reasoning in two ways: it slowed processing non-specifically when the demands of working memory increased and it augmented validation time depending on the difficulty in generating and/or manipulating mental representations by the central executive." @default.
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- W4234104381 date "2010-01-01" @default.
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- W4234104381 title "Hypnosedatives and anxiolytics" @default.
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- W4234104381 doi "https://doi.org/10.1016/s0378-6080(10)32005-8" @default.
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