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- W4234311122 abstract "The levels of activity of hexokinase, phosphoglucomutase, uridine diphosphoglucose pyrophosphorylase, and uridine diphosphoglucose dehydrogenase, which are involved in the synthesis of glucuronic acid, and the levels of glucuronosyltransferase and β-glucuronidase, which are involved in its metabolism, were studied in connective tissue from polyvinyl sponge implants from sham-operated and adrenalectomized rats which had received replacement therapy of individual steroids.The levels of activity of these enzymes were significantly increased in sham-operated rats which had been treated with corticosterone, cortisone, or hydrocortisone. In adrenalectomized animals, the increased or decreased enzyme activities were restored to normal levels by therapy with corticosterone, cortisone, or hydrocortisone. In some cases there was an over-correction at the particular level of hormone treatment. In both sham-operated and adrenalectomized animals, treatment with deoxycorticosterone, progesterone, or Reichstein's substance S frequently, but not always, resulted in little or no change in activity of the enzymes." @default.
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- W4234311122 date "1967-08-01" @default.
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- W4234311122 title "THE METABOLISM OF MUCOPOLYSACCHARIDES: III. THE EFFECT OF ADRENOCORTICAL HORMONES ON ENZYMES INVOLVED IN GLUCURONIDE SYNTHESIS AND METABOLISM IN CONNECTIVE TISSUE" @default.
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- W4234311122 doi "https://doi.org/10.1139/o67-145" @default.
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