Matches in SemOpenAlex for { <https://semopenalex.org/work/W4234336306> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4234336306 abstract "Abstract Background Acute respiratory distress syndrome (ARDS) following cardiac arrest is common and associated with in-hospital mortality. We aimed to investigate whether lung compliance during targeted temperature management is associated with neurological outcome in patients with ARDS after out-of-hospital cardiac arrest (OHCA).Methods This observational study was conducted in the emergency intensive care unit from January 2011 to April 2019 using data from a prospective patient registry. Adult patients (age ≥18 years) who survived non-traumatic OHCA and subsequently developed ARDS based on the Berlin definition were included. Mechanical ventilator parameters such as peak inspiratory pressure, tidal volume, minute ventilation, positive end expiratory pressure, and compliance were recorded for 7 days or until death, and categorized as maximum, median, and minimum. The primary outcome was favorable neurological outcome defined as Cerebral Performance Category score 1 or 2 at hospital discharge.Results Of 246 OHCA survivors, 119 (48.4%) patients developed ARDS. A favorable neurologic outcome was observed in 23 (19.3%). Patients with favorable outcome had significantly higher lung compliance (38.6 cm H 2 O vs 27.5 cm H 2 O), lower inspiratory pressure (12.0 cm H 2 O vs 16.0 cm H 2 O), and lower peak inspiratory pressure (17.0 cm H 2 O vs 21.0 cm H 2 O) than those with poor neurologic outcome (all P <0.01). In time-dependent cox regression models, all maximum (hazard ratio [HR] 1.05, 95% confidence interval [CI] 1.03-1.08), minimum (HR 1.08, 95% CI 1.04 – 1.12), and median (HR 1.06, 95% CI 1.03-1.10) compliances were independently associated with good neurologic outcome. Median compliance > 31.4 mL/cm H 2 O at day 1 had the highest area under the receiver operating characteristic curve (0.732) with positive predictive value of 90%.Conclusion Lung compliance may be an early predictor of neurologic intact survival in patients with ARDS following cardiac arrest." @default.
- W4234336306 created "2022-05-12" @default.
- W4234336306 creator A5007502903 @default.
- W4234336306 creator A5022010111 @default.
- W4234336306 creator A5034234965 @default.
- W4234336306 creator A5044207369 @default.
- W4234336306 creator A5058927747 @default.
- W4234336306 creator A5082140629 @default.
- W4234336306 date "2020-01-10" @default.
- W4234336306 modified "2023-09-26" @default.
- W4234336306 title "Impact of lung compliance on neurological outcome in patients with acute respiratory distress syndrome following out-of-hospital cardiac arrest" @default.
- W4234336306 doi "https://doi.org/10.21203/rs.2.20594/v1" @default.
- W4234336306 hasPublicationYear "2020" @default.
- W4234336306 type Work @default.
- W4234336306 citedByCount "0" @default.
- W4234336306 crossrefType "posted-content" @default.
- W4234336306 hasAuthorship W4234336306A5007502903 @default.
- W4234336306 hasAuthorship W4234336306A5022010111 @default.
- W4234336306 hasAuthorship W4234336306A5034234965 @default.
- W4234336306 hasAuthorship W4234336306A5044207369 @default.
- W4234336306 hasAuthorship W4234336306A5058927747 @default.
- W4234336306 hasAuthorship W4234336306A5082140629 @default.
- W4234336306 hasBestOaLocation W42343363061 @default.
- W4234336306 hasConcept C126322002 @default.
- W4234336306 hasConcept C127413603 @default.
- W4234336306 hasConcept C136936797 @default.
- W4234336306 hasConcept C141983124 @default.
- W4234336306 hasConcept C164705383 @default.
- W4234336306 hasConcept C177713679 @default.
- W4234336306 hasConcept C200457457 @default.
- W4234336306 hasConcept C207103383 @default.
- W4234336306 hasConcept C2776348555 @default.
- W4234336306 hasConcept C2776376669 @default.
- W4234336306 hasConcept C2777080012 @default.
- W4234336306 hasConcept C2777257755 @default.
- W4234336306 hasConcept C2777714996 @default.
- W4234336306 hasConcept C2987404301 @default.
- W4234336306 hasConcept C42219234 @default.
- W4234336306 hasConcept C44249647 @default.
- W4234336306 hasConcept C534529494 @default.
- W4234336306 hasConcept C71924100 @default.
- W4234336306 hasConcept C78519656 @default.
- W4234336306 hasConceptScore W4234336306C126322002 @default.
- W4234336306 hasConceptScore W4234336306C127413603 @default.
- W4234336306 hasConceptScore W4234336306C136936797 @default.
- W4234336306 hasConceptScore W4234336306C141983124 @default.
- W4234336306 hasConceptScore W4234336306C164705383 @default.
- W4234336306 hasConceptScore W4234336306C177713679 @default.
- W4234336306 hasConceptScore W4234336306C200457457 @default.
- W4234336306 hasConceptScore W4234336306C207103383 @default.
- W4234336306 hasConceptScore W4234336306C2776348555 @default.
- W4234336306 hasConceptScore W4234336306C2776376669 @default.
- W4234336306 hasConceptScore W4234336306C2777080012 @default.
- W4234336306 hasConceptScore W4234336306C2777257755 @default.
- W4234336306 hasConceptScore W4234336306C2777714996 @default.
- W4234336306 hasConceptScore W4234336306C2987404301 @default.
- W4234336306 hasConceptScore W4234336306C42219234 @default.
- W4234336306 hasConceptScore W4234336306C44249647 @default.
- W4234336306 hasConceptScore W4234336306C534529494 @default.
- W4234336306 hasConceptScore W4234336306C71924100 @default.
- W4234336306 hasConceptScore W4234336306C78519656 @default.
- W4234336306 hasLocation W42343363061 @default.
- W4234336306 hasOpenAccess W4234336306 @default.
- W4234336306 hasPrimaryLocation W42343363061 @default.
- W4234336306 hasRelatedWork W11630410 @default.
- W4234336306 hasRelatedWork W14331486 @default.
- W4234336306 hasRelatedWork W17233218 @default.
- W4234336306 hasRelatedWork W17531768 @default.
- W4234336306 hasRelatedWork W1793858 @default.
- W4234336306 hasRelatedWork W20702651 @default.
- W4234336306 hasRelatedWork W20770126 @default.
- W4234336306 hasRelatedWork W2110253 @default.
- W4234336306 hasRelatedWork W2828659 @default.
- W4234336306 hasRelatedWork W7804516 @default.
- W4234336306 isParatext "false" @default.
- W4234336306 isRetracted "false" @default.
- W4234336306 workType "article" @default.