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- W4234431325 abstract "This chapter discusses sotalol, which is an odorless, white crystalline solid. Optical rotations of the two pure enantiomers of sotalol HCl are obtained using a Perkin Elmer Model 241 polarimeter. The rotations are measured in a 10 cm cell (water as solvent) at the sodium D-line (589 nm). Sotalol HCl is freely soluble in water and only slightly soluble in chloroform. A number of methods are described in this chapter for the analysis of sotalol. Some methods that have been utilized for the analysis of sotalol in urine are also discussed in the chapter. Most nonstereospecific HPLC assays utilize reverse-phase chromatography with isocratic flow. The enantiomers of sotalol utilize HPLC methods; these methods employ either chiral stationary phases or pre-column derivatization with a homochiral reagent." @default.
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- W4234431325 date "1992-01-01" @default.
- W4234431325 modified "2023-09-25" @default.
- W4234431325 title "Sotalol" @default.
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- W4234431325 doi "https://doi.org/10.1016/s0099-5428(08)60400-1" @default.
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