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- W4234433467 abstract "The synthesis of N, N′-bis-{2-[(5-bromo-2-[1-14C]hexyl-1H-benz[de]isoquinolin-1,3(2H)-dion-6-yl)amino]ethyl}hexanediamide from 1-[1-14C]-hexylamine and 4-chloro-1,8-naphthalic anhydride is described. The anhydride is first converted to the 4-chloro-N-[1-14C]hexyl-1,8-naphthalimide (2) by condensation with 1-[1-14C]-hexylamine, and the chlorine is then displaced with ethylenediamine to give the 4-(2-aminoethylamino-N-[1-14C]hexyl-1,8-naphthalimide (3). Coupling of this monomeric naphthalimide with adipoyl chloride affords the dimeric naphthalimide (4) which is brominated regiospecifically with elemental bromine in carbon tetrachloride to afford the title compound (5)." @default.
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- W4234433467 date "1996-07-01" @default.
- W4234433467 modified "2023-10-08" @default.
- W4234433467 title "Photochemically activated antiviral halogenated 1,8-naphthalimides: Synthesis of N,N-BIS-{2-[(5-bromo-2-[1-14C]hexyl-1H-benz[DE]isoquinolin-1,3(2H)-dion-6-YL)amino]ethyl}hexanediamide" @default.
- W4234433467 doi "https://doi.org/10.1002/(sici)1099-1344(199607)38:7<607::aid-jlcr875>3.3.co;2-h" @default.
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