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- W4234541239 abstract "We appreciate Dr. Lee’s review of anatomic data regarding the optic chiasm. In particular, Dr. Lee provides a detailed summary of the functional anatomy of the chiasm in primates. Consequences on the visual field of compressions by tumors of the pituitary are not solely a function of the anatomy of the chiasm but also depend on other factors, such as variations in the position of the chiasm relative to the sella turcica. In antero-positioned chiasm, compression by the suprasellar extension of a pituitary adenoma will most likely affect the posterior part of the chiasm. Conversely, when the chiasm is retropositioned, consequences of suprasellar tumors will most likely affect the anterior part of the chiasm. Dynamics of tumor growth also play an important role in chiasmal lesions. In acromegaly, relatively rapid suprasellar extensions from the pituitary are often irregular, leading to visual field defects often less systematized than in other tumors. Moreover, local vascular factors may play a role in lesions of the chiasm. In our survey of 307 cases of acromegaly, we have observed 24 unilateral visual field defects. We are confident that Goldmann perimetry performed by trained technicians has enough sensitivity to detect defects of the macular bundle contralateral to a superotemporal defect. Although we have observed typical Traquair’s junctional scotoma in other causes of pituitary tumors, this type of visual field defect was not found in our series of patients with acromegaly." @default.
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- W4234541239 date "2001-05-01" @default.
- W4234541239 modified "2023-09-30" @default.
- W4234541239 title "Author’s reply" @default.
- W4234541239 doi "https://doi.org/10.1016/s0161-6420(00)00557-1" @default.
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