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- W4234583142 abstract "Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. After male human subjects were infused with [ 14 C]‐dopamine, approximately 75% of the infused radioactive dose was metabolized. Major metabolites identified include 3‐methoxy‐4‐hydroxyphenyl acetic acid, 3‐methoxytyramine, 3,4‐dihydroxyphenyl acetic acid, 3,4‐dihydroxy‐phenylethanol, 3‐methoxy‐4‐hydroxyphenylethanol, and their conjugates. The remaining 25% of the infused radioactive dose was identified as norepinephrine. Secondary metabolites included 3,4‐dihydroxymandelic acid, normetanephrine, vanillylmandelic acid, and vanillic acid. 3,4‐Dihydroxyphenylglycol and 3‐methyl‐4‐hydroxyphenylglycol were observed as minor metabolites." @default.
- W4234583142 created "2022-05-12" @default.
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- W4234583142 date "2013-10-13" @default.
- W4234583142 modified "2023-09-26" @default.
- W4234583142 title "Dopamine" @default.
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- W4234583142 doi "https://doi.org/10.1002/9781118541203.xen267" @default.
- W4234583142 hasPublicationYear "2013" @default.
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