Matches in SemOpenAlex for { <https://semopenalex.org/work/W4234591489> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4234591489 endingPage "AB55" @default.
- W4234591489 startingPage "AB55" @default.
- W4234591489 abstract "Patients with penicillin allergy labels often receive alternative antibiotics for peri-operative prophylaxis, as opposed to first-line cephalosporins (cefazolin/cefuroxime). Provider misconceptions about the risk of cross-reactivity likely drive this prescribing behavior, which is problematic because due to association with an increased risk of surgical site infections. We created and implemented an algorithm intended to guide appropriate peri-operative antibiotic selection in the setting of penicillin allergy. A multidisciplinary group developed the algorithm for antibiotic selection in penicillin-allergic surgical patients, to optimize cephalosporin use. The percentage of patients receiving a first-line cephalosporin was compared before and after algorithm utilization. Safety was assessed via chart reviews performed on any patient who received epinephrine in the operating room or diphenhydramine in the twenty-four hours post-operatively, as surrogates for immediate and delayed reactions to cephalosporin administration. Between September 2016 and May 2019, 7.9% of surgical patients had documented penicillin allergy - 38% were not detailed further, 27% were consistent with type I hypersensitivity, 21% rash or itching, 7% a side effect, 5% unknown, and 1% consistent with severe delayed reactions. At baseline, ∼22% of these patients received a cephalosporin, with an increase to >80% following algorithm implementation (p<0.0000001). No immediate allergic reactions requiring epinephrine were identified; one patient had a delayed rash that did not require cephalosporin discontinuation and three patients received diphenhydramine for itching” without rash in the setting of concomitant narcotic administration. Using a streamlined algorithm, we were able to significantly limit use of second-line alternatives in penicillin-allergic surgical patients without severe adverse reactions." @default.
- W4234591489 created "2022-05-12" @default.
- W4234591489 creator A5001656235 @default.
- W4234591489 creator A5048910013 @default.
- W4234591489 creator A5050637738 @default.
- W4234591489 creator A5052160637 @default.
- W4234591489 creator A5058249059 @default.
- W4234591489 creator A5080765731 @default.
- W4234591489 date "2020-02-01" @default.
- W4234591489 modified "2023-10-16" @default.
- W4234591489 title "A streamlined approach to optimize perioperative antibiotic prophylaxis in the setting of penicillin allergy labels" @default.
- W4234591489 doi "https://doi.org/10.1016/j.jaci.2019.12.696" @default.
- W4234591489 hasPublicationYear "2020" @default.
- W4234591489 type Work @default.
- W4234591489 citedByCount "1" @default.
- W4234591489 countsByYear W42345914892023 @default.
- W4234591489 crossrefType "journal-article" @default.
- W4234591489 hasAuthorship W4234591489A5001656235 @default.
- W4234591489 hasAuthorship W4234591489A5048910013 @default.
- W4234591489 hasAuthorship W4234591489A5050637738 @default.
- W4234591489 hasAuthorship W4234591489A5052160637 @default.
- W4234591489 hasAuthorship W4234591489A5058249059 @default.
- W4234591489 hasAuthorship W4234591489A5080765731 @default.
- W4234591489 hasBestOaLocation W42345914891 @default.
- W4234591489 hasConcept C16005928 @default.
- W4234591489 hasConcept C174802600 @default.
- W4234591489 hasConcept C177713679 @default.
- W4234591489 hasConcept C203014093 @default.
- W4234591489 hasConcept C207480886 @default.
- W4234591489 hasConcept C2775933838 @default.
- W4234591489 hasConcept C2778353156 @default.
- W4234591489 hasConcept C2778570526 @default.
- W4234591489 hasConcept C2779060952 @default.
- W4234591489 hasConcept C31174226 @default.
- W4234591489 hasConcept C42219234 @default.
- W4234591489 hasConcept C501593827 @default.
- W4234591489 hasConcept C64778159 @default.
- W4234591489 hasConcept C71924100 @default.
- W4234591489 hasConcept C86803240 @default.
- W4234591489 hasConcept C89423630 @default.
- W4234591489 hasConceptScore W4234591489C16005928 @default.
- W4234591489 hasConceptScore W4234591489C174802600 @default.
- W4234591489 hasConceptScore W4234591489C177713679 @default.
- W4234591489 hasConceptScore W4234591489C203014093 @default.
- W4234591489 hasConceptScore W4234591489C207480886 @default.
- W4234591489 hasConceptScore W4234591489C2775933838 @default.
- W4234591489 hasConceptScore W4234591489C2778353156 @default.
- W4234591489 hasConceptScore W4234591489C2778570526 @default.
- W4234591489 hasConceptScore W4234591489C2779060952 @default.
- W4234591489 hasConceptScore W4234591489C31174226 @default.
- W4234591489 hasConceptScore W4234591489C42219234 @default.
- W4234591489 hasConceptScore W4234591489C501593827 @default.
- W4234591489 hasConceptScore W4234591489C64778159 @default.
- W4234591489 hasConceptScore W4234591489C71924100 @default.
- W4234591489 hasConceptScore W4234591489C86803240 @default.
- W4234591489 hasConceptScore W4234591489C89423630 @default.
- W4234591489 hasIssue "2" @default.
- W4234591489 hasLocation W42345914891 @default.
- W4234591489 hasOpenAccess W4234591489 @default.
- W4234591489 hasPrimaryLocation W42345914891 @default.
- W4234591489 hasRelatedWork W1717471183 @default.
- W4234591489 hasRelatedWork W2042715670 @default.
- W4234591489 hasRelatedWork W2282266379 @default.
- W4234591489 hasRelatedWork W2351066668 @default.
- W4234591489 hasRelatedWork W2413821946 @default.
- W4234591489 hasRelatedWork W2801674685 @default.
- W4234591489 hasRelatedWork W2914742672 @default.
- W4234591489 hasRelatedWork W4200268270 @default.
- W4234591489 hasRelatedWork W4211095142 @default.
- W4234591489 hasRelatedWork W4285741154 @default.
- W4234591489 hasVolume "145" @default.
- W4234591489 isParatext "false" @default.
- W4234591489 isRetracted "false" @default.
- W4234591489 workType "article" @default.