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- W4234592425 abstract "The genomes of higher eukaryotes are not homogeneous in terms of structure or function. Many examples of chromosomal regions particularly prone to involvement in aberrations have been reported. The molecular structures of some of these regions have now been determined, most notably the folate-sensitive fragile sites and FRA16B—a distamycin A-sensitive fragile site. In addition, a number of cytological studies suggest that telomeric sequences can in some circumstances be involved in chromosomal aberrations more frequently than expected. Here, the roles of telomeric DNA sequences, both terminal and interstitial, and telomerase in chromosomal aberration formation are reviewed." @default.
- W4234592425 created "2022-05-12" @default.
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- W4234592425 date "1998-08-01" @default.
- W4234592425 modified "2023-10-18" @default.
- W4234592425 title "Involvement of telomeric sequences in chromosomal aberrations" @default.
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- W4234592425 doi "https://doi.org/10.1016/s0027-5107(98)00114-6" @default.
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