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- W4234857758 abstract "The association of the Philadelphia chromosome with chronic myelocytic leukemia is well known, but the association of the Christchurch chromosome with chronic lymphocytic leukemia, the Philadelphia (or Philadelphia-like) chromosome with acute myeloblastic leukemia, the Melbourne chromosome with malignant lymphomas, the Madison chromosome with nonepithelial tumors, a long marker chromosome with testicular tumors, and double minute chromatin bodies with childhood tumors are not widely known or agreed upon. These chromosomal abnormalities are but a few of the many reported in the literature. Karyotypic changes are not always seen at the level of the light microscope. Whether chromosomal abnormalities are important in the initiation of neoplasia or not, their identification may be useful in the diagnosis, prognosis, and therapeutic management of some patients with cancer." @default.
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- W4234857758 date "1969-08-18" @default.
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- W4234857758 title "Chromosomal abnormalities in certain human malignancies. A review" @default.
- W4234857758 doi "https://doi.org/10.1001/jama.209.7.1063" @default.
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