Matches in SemOpenAlex for { <https://semopenalex.org/work/W4234869142> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W4234869142 endingPage "343" @default.
- W4234869142 startingPage "340" @default.
- W4234869142 abstract "A rapid, simple and reliable high-performance liquid chromatography (HPLC) column-switching method with UV detection (270 nm) for the simultaneous determination of propentofylline and its metabolites in human and rat sera was developed. The method involves direct injection of serum onto an HPLC column, which contains a shielded hydrophobic stationary phase for the separation of analytes from proteins in serum, and then loading the analytes onto a short octadecylsilylated silica gel (ODS) column using a switching valve. Propentofylline and its three metabolites in serum were separated from the serum components within 30 min after the injection. The detection limits (S/N = 3) of analytes spiked in human and rat sera ranged from 0.08 to 0.57 nmol/mL, and the net volume of serum used was 20 µL. The relative standard deviations for within- and between-day variations using rat serum were less than 4.3 and 5.6%, respectively. The method was used to determine propentofylline and its main metabolites in rat serum after a single intravenous dose of propentofylline (5 mg/kg). Copyright © 1999 John Wiley & Sons, Ltd." @default.
- W4234869142 created "2022-05-12" @default.
- W4234869142 creator A5010913202 @default.
- W4234869142 creator A5023025894 @default.
- W4234869142 creator A5038410513 @default.
- W4234869142 creator A5048191593 @default.
- W4234869142 creator A5070036246 @default.
- W4234869142 creator A5083539928 @default.
- W4234869142 date "1999-08-01" @default.
- W4234869142 modified "2023-09-25" @default.
- W4234869142 title "Simple and rapid high‐performance liquid chromatography analysis of propentofylline and its main metabolites in serum using a direct injection technique" @default.
- W4234869142 doi "https://doi.org/10.1002/(sici)1099-0801(199908)13:5<340::aid-bmc883>3.3.co;2-m" @default.
- W4234869142 hasPublicationYear "1999" @default.
- W4234869142 type Work @default.
- W4234869142 citedByCount "0" @default.
- W4234869142 crossrefType "journal-article" @default.
- W4234869142 hasAuthorship W4234869142A5010913202 @default.
- W4234869142 hasAuthorship W4234869142A5023025894 @default.
- W4234869142 hasAuthorship W4234869142A5038410513 @default.
- W4234869142 hasAuthorship W4234869142A5048191593 @default.
- W4234869142 hasAuthorship W4234869142A5070036246 @default.
- W4234869142 hasAuthorship W4234869142A5083539928 @default.
- W4234869142 hasConcept C10390740 @default.
- W4234869142 hasConcept C119128265 @default.
- W4234869142 hasConcept C179998833 @default.
- W4234869142 hasConcept C185592680 @default.
- W4234869142 hasConcept C43617362 @default.
- W4234869142 hasConceptScore W4234869142C10390740 @default.
- W4234869142 hasConceptScore W4234869142C119128265 @default.
- W4234869142 hasConceptScore W4234869142C179998833 @default.
- W4234869142 hasConceptScore W4234869142C185592680 @default.
- W4234869142 hasConceptScore W4234869142C43617362 @default.
- W4234869142 hasIssue "5" @default.
- W4234869142 hasLocation W42348691421 @default.
- W4234869142 hasOpenAccess W4234869142 @default.
- W4234869142 hasPrimaryLocation W42348691421 @default.
- W4234869142 hasRelatedWork W1913148260 @default.
- W4234869142 hasRelatedWork W1964888264 @default.
- W4234869142 hasRelatedWork W1973892552 @default.
- W4234869142 hasRelatedWork W2006820847 @default.
- W4234869142 hasRelatedWork W2091141891 @default.
- W4234869142 hasRelatedWork W2101836819 @default.
- W4234869142 hasRelatedWork W2154588018 @default.
- W4234869142 hasRelatedWork W2382109194 @default.
- W4234869142 hasRelatedWork W2393257291 @default.
- W4234869142 hasRelatedWork W2601524031 @default.
- W4234869142 hasVolume "13" @default.
- W4234869142 isParatext "false" @default.
- W4234869142 isRetracted "false" @default.
- W4234869142 workType "article" @default.