FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4235200804> ?p ?o ?g. }

• W4235200804 endingPage "485" @default.
• W4235200804 startingPage "484" @default.
• W4235200804 abstract "We thank Drs Buzzetti, D'Amico, and Addis for their interest in our paper.1Simons FER Villa JR Lee BW Teper AM Lyttle B Aristizabal G et al.Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study.J Pediatr. 2001; 138: 694-698Abstract Full Text Full Text PDF PubMed Scopus (174) Google Scholar Information about the number of children included and excluded during the prerandomization run-in is not typically reported in prospective, double-blind, controlled clinical trials in children with asthma.2Knorr B Matz J Bernstein JA Nguyen H Seidenberg BC Reiss TF et al.Montelukast for chronic asthma in 6- to 14-year-old children. A randomized, double-blind trial.JAMA. 1998; 279: 1181-1186Crossref PubMed Scopus (509) Google Scholar, 3Childhood Asthma Management Program Research Group Long-term effects of budesonide or nedocromil in children with asthma.N Engl J Med. 2000; 343: 1054-1063Crossref PubMed Scopus (1281) Google Scholar, 4Simons FER Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group A comparison of beclomethasone, salmeterol, and placebo in children with asthma.N Engl J Med. 1997; 337: 1659-1665Crossref PubMed Scopus (299) Google Scholar The run-in period is essentially a baseline screening period characterized not only by evaluation of inclusion and exclusion criteria, but also by teaching and assessment of each child, particularly with regard to ability to use inhaler devices and peak flow meters and to perform spirometry. In some centers, children are rigorously screened before entering the run-in period and the rate of exclusion before randomization is low. In other centers, children are minimally screened before entering the run-in period, and the rate of exclusion before randomization is high. Our reasons for excluding the 46 children after randomization are clearly outlined in the paper and are valid.1Simons FER Villa JR Lee BW Teper AM Lyttle B Aristizabal G et al.Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study.J Pediatr. 2001; 138: 694-698Abstract Full Text Full Text PDF PubMed Scopus (174) Google Scholar We state clearly in our paper that the effect of montelukast on forced expiratory volume in one second (FEV1) is “small” or “modest”1Simons FER Villa JR Lee BW Teper AM Lyttle B Aristizabal G et al.Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study.J Pediatr. 2001; 138: 694-698Abstract Full Text Full Text PDF PubMed Scopus (174) Google Scholar; however, it is consistent with clinically relevant endpoints used to characterize asthma control, including a 23% decrease in asthma exacerbations. The mean FEV1 values obscure the fact that some children responded well to montelukast, while others did not (Figure). The data from Santanello et al5Santanello NC Zhang J Seidenberg B Reiss TF Barber BL What are minimal important changes for asthma measures in a clinical trial?.Eur Respir J. 1999; 14: 23-27Crossref PubMed Scopus (206) Google Scholar to which Buzzetti et al refer, are based on an absolute increase in FEV1 in liters in adults and are not applicable to children. Our study was the first to demonstrate any significant benefit of adding any medication from any class to an inhaled glucocorticoid in children with persistent asthma. The challenge for the future is to identify children who might benefit most from a leukotriene modifier." @default.
• W4235200804 created "2022-05-12" @default.
• W4235200804 creator A5014888902 @default.
• W4235200804 creator A5087600572 @default.
• W4235200804 creator A5088258773 @default.
• W4235200804 date "2002-04-01" @default.
• W4235200804 modified "2023-10-14" @default.
• W4235200804 title "Reply" @default.
• W4235200804 cites W2073817403 @default.
• W4235200804 cites W2087410653 @default.
• W4235200804 cites W2109215965 @default.
• W4235200804 cites W2337667511 @default.
• W4235200804 cites W2594805288 @default.
• W4235200804 doi "https://doi.org/10.1067/mpd.2002.120829" @default.
• W4235200804 hasPublicationYear "2002" @default.
• W4235200804 type Work @default.
• W4235200804 citedByCount "2" @default.
• W4235200804 countsByYear W42352008042012 @default.
• W4235200804 crossrefType "journal-article" @default.
• W4235200804 hasAuthorship W4235200804A5014888902 @default.
• W4235200804 hasAuthorship W4235200804A5087600572 @default.
• W4235200804 hasAuthorship W4235200804A5088258773 @default.
• W4235200804 hasConcept C126322002 @default.
• W4235200804 hasConcept C142724271 @default.
• W4235200804 hasConcept C168563851 @default.
• W4235200804 hasConcept C17744445 @default.
• W4235200804 hasConcept C1862650 @default.
• W4235200804 hasConcept C187212893 @default.
• W4235200804 hasConcept C199539241 @default.
• W4235200804 hasConcept C204787440 @default.
• W4235200804 hasConcept C27081682 @default.
• W4235200804 hasConcept C2776042228 @default.
• W4235200804 hasConcept C2776136866 @default.
• W4235200804 hasConcept C2776322731 @default.
• W4235200804 hasConcept C2776719499 @default.
• W4235200804 hasConcept C2777596629 @default.
• W4235200804 hasConcept C2779473830 @default.
• W4235200804 hasConcept C2780261241 @default.
• W4235200804 hasConcept C2780333948 @default.
• W4235200804 hasConcept C71924100 @default.
• W4235200804 hasConcept C83867959 @default.
• W4235200804 hasConceptScore W4235200804C126322002 @default.
• W4235200804 hasConceptScore W4235200804C142724271 @default.
• W4235200804 hasConceptScore W4235200804C168563851 @default.
• W4235200804 hasConceptScore W4235200804C17744445 @default.
• W4235200804 hasConceptScore W4235200804C1862650 @default.
• W4235200804 hasConceptScore W4235200804C187212893 @default.
• W4235200804 hasConceptScore W4235200804C199539241 @default.
• W4235200804 hasConceptScore W4235200804C204787440 @default.
• W4235200804 hasConceptScore W4235200804C27081682 @default.
• W4235200804 hasConceptScore W4235200804C2776042228 @default.
• W4235200804 hasConceptScore W4235200804C2776136866 @default.
• W4235200804 hasConceptScore W4235200804C2776322731 @default.
• W4235200804 hasConceptScore W4235200804C2776719499 @default.
• W4235200804 hasConceptScore W4235200804C2777596629 @default.
• W4235200804 hasConceptScore W4235200804C2779473830 @default.
• W4235200804 hasConceptScore W4235200804C2780261241 @default.
• W4235200804 hasConceptScore W4235200804C2780333948 @default.
• W4235200804 hasConceptScore W4235200804C71924100 @default.
• W4235200804 hasConceptScore W4235200804C83867959 @default.
• W4235200804 hasIssue "4" @default.
• W4235200804 hasLocation W42352008041 @default.
• W4235200804 hasOpenAccess W4235200804 @default.
• W4235200804 hasPrimaryLocation W42352008041 @default.
• W4235200804 hasRelatedWork W1975167242 @default.
• W4235200804 hasRelatedWork W198494087 @default.
• W4235200804 hasRelatedWork W2058386143 @default.
• W4235200804 hasRelatedWork W2079098458 @default.
• W4235200804 hasRelatedWork W2093334569 @default.
• W4235200804 hasRelatedWork W2109586110 @default.
• W4235200804 hasRelatedWork W2444479270 @default.
• W4235200804 hasRelatedWork W2900689585 @default.
• W4235200804 hasRelatedWork W2931957328 @default.
• W4235200804 hasRelatedWork W2990063982 @default.
• W4235200804 hasVolume "140" @default.
• W4235200804 isParatext "false" @default.
• W4235200804 isRetracted "false" @default.
• W4235200804 workType "article" @default.