Matches in SemOpenAlex for { <https://semopenalex.org/work/W4235204030> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4235204030 abstract "Abstract Backgrounds: Tolvaptan significantly increases urine volume in acute decompensated heart failure (ADHF); serum sodium level increases due to aquaresis in almost all cases. We aimed to elucidate clinical factors associated with hypernatremia in ADHF patients treated with tolvaptan. Methods: We enrolled 117 ADHF patients treated with tolvaptan in addition to standard therapy. We examined differences in clinical factors at baseline between patients with and without hypernatremia in the initial three days of hospitalization. Results: Systolic (p=0.045) and diastolic (p=0.004) blood pressure, serum sodium level (p=0.002), and negative water balance (p=0.036) were significantly higher and serum potassium level (p=0.026) was significantly lower on admission day in patients with hypernatremia (n=22). In multivariate regression analysis, hypernatremia was associated with low serum potassium level (p=0.034). Among patients with serum potassium level ≤3.8 mEq/L, the cutoff value obtained using receiver operating characteristic curve analysis, those with hypernatremia related to tolvaptan treatment showed significantly higher diastolic blood pressure on admission day (p=0.004). Conclusion: In tolvaptan treatment combined with standard therapy in ADHF patients, serum potassium level ≤ 3.8mEq/L may be a determinant factor for hypernatremia development. Among hypokalemic patients, those with higher diastolic blood pressure on admission may be carefully managed to prevent hypernatremia." @default.
- W4235204030 created "2022-05-12" @default.
- W4235204030 creator A5002383968 @default.
- W4235204030 creator A5002800331 @default.
- W4235204030 creator A5006564484 @default.
- W4235204030 creator A5014433253 @default.
- W4235204030 creator A5016012342 @default.
- W4235204030 creator A5019633750 @default.
- W4235204030 creator A5038266195 @default.
- W4235204030 creator A5038600676 @default.
- W4235204030 creator A5052712144 @default.
- W4235204030 creator A5074971081 @default.
- W4235204030 date "2020-10-14" @default.
- W4235204030 modified "2023-09-27" @default.
- W4235204030 title "Tolvaptan-induced hypernatremia related to low serum potassium level accompanying high blood pressure in patients with acute decompensated heart failure." @default.
- W4235204030 doi "https://doi.org/10.21203/rs.3.rs-39563/v3" @default.
- W4235204030 hasPublicationYear "2020" @default.
- W4235204030 type Work @default.
- W4235204030 citedByCount "0" @default.
- W4235204030 crossrefType "posted-content" @default.
- W4235204030 hasAuthorship W4235204030A5002383968 @default.
- W4235204030 hasAuthorship W4235204030A5002800331 @default.
- W4235204030 hasAuthorship W4235204030A5006564484 @default.
- W4235204030 hasAuthorship W4235204030A5014433253 @default.
- W4235204030 hasAuthorship W4235204030A5016012342 @default.
- W4235204030 hasAuthorship W4235204030A5019633750 @default.
- W4235204030 hasAuthorship W4235204030A5038266195 @default.
- W4235204030 hasAuthorship W4235204030A5038600676 @default.
- W4235204030 hasAuthorship W4235204030A5052712144 @default.
- W4235204030 hasAuthorship W4235204030A5074971081 @default.
- W4235204030 hasBestOaLocation W42352040301 @default.
- W4235204030 hasConcept C126322002 @default.
- W4235204030 hasConcept C164705383 @default.
- W4235204030 hasConcept C178790620 @default.
- W4235204030 hasConcept C185592680 @default.
- W4235204030 hasConcept C2778198053 @default.
- W4235204030 hasConcept C2778864100 @default.
- W4235204030 hasConcept C2779295919 @default.
- W4235204030 hasConcept C2780615674 @default.
- W4235204030 hasConcept C537181965 @default.
- W4235204030 hasConcept C71924100 @default.
- W4235204030 hasConcept C84393581 @default.
- W4235204030 hasConceptScore W4235204030C126322002 @default.
- W4235204030 hasConceptScore W4235204030C164705383 @default.
- W4235204030 hasConceptScore W4235204030C178790620 @default.
- W4235204030 hasConceptScore W4235204030C185592680 @default.
- W4235204030 hasConceptScore W4235204030C2778198053 @default.
- W4235204030 hasConceptScore W4235204030C2778864100 @default.
- W4235204030 hasConceptScore W4235204030C2779295919 @default.
- W4235204030 hasConceptScore W4235204030C2780615674 @default.
- W4235204030 hasConceptScore W4235204030C537181965 @default.
- W4235204030 hasConceptScore W4235204030C71924100 @default.
- W4235204030 hasConceptScore W4235204030C84393581 @default.
- W4235204030 hasLocation W42352040301 @default.
- W4235204030 hasLocation W42352040302 @default.
- W4235204030 hasLocation W42352040303 @default.
- W4235204030 hasOpenAccess W4235204030 @default.
- W4235204030 hasPrimaryLocation W42352040301 @default.
- W4235204030 hasRelatedWork W2066998092 @default.
- W4235204030 hasRelatedWork W2124095484 @default.
- W4235204030 hasRelatedWork W2125804349 @default.
- W4235204030 hasRelatedWork W2508040870 @default.
- W4235204030 hasRelatedWork W3097860952 @default.
- W4235204030 hasRelatedWork W4234961914 @default.
- W4235204030 hasRelatedWork W4237701906 @default.
- W4235204030 hasRelatedWork W4244899550 @default.
- W4235204030 hasRelatedWork W4366988282 @default.
- W4235204030 hasRelatedWork W2514587071 @default.
- W4235204030 isParatext "false" @default.
- W4235204030 isRetracted "false" @default.
- W4235204030 workType "article" @default.