FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4235288735> ?p ?o ?g. }

• W4235288735 endingPage "S54" @default.
• W4235288735 startingPage "S53" @default.
• W4235288735 abstract "Background & Aims: Budd–Chiari syndrome (BCS) is an uncommon disorder defined as a hepatic venous outflow obstruction at any level between the hepatic veins and the right atrium. It usually involves thrombosis of the hepatic veins and/or the intrahepatic or suprahepatic inferior vena cava. Treatment of BCS includes medical, interventional radiological (TIPS) and surgical interventions. As the disease is rare, there is limited data regarding the long term survival of patients undergoing TIPS. The aim of this study was to report our single centre long term follow-up results of patients with BCS who underwent TIPS.Methods: 42 BCS patients underwent TIPS with covered stent between 2004 and 2014. Retrospective analysis was performed regarding the presenting symptoms and laboratory workup pre- and post-TIPS, etiology of BCS, extent of thrombosis, status of varices, therapeutic interventions, complications, symptom relief and overall outcome.Results: 16 women and 26 men with a mean age of 40 years (range: 14–60 years) at time of diagnosis were included. Myeloproliferative disorder and JAK 2 mutation were the commonest etiology followed by MTHFR mutation. The cause of BCS was unclear in 24 patients. There was significant improvement in ascites, GI bleed, HRS and transaminase levels post TIPS. 3 patients required a TIPS plasty and one patient underwent TIPS reduction. There were 11 deaths over the follow-up period, 4 within one month, 2 within six months and the rest after 3 years following TIPS. Median duration from clinical presentation to TIPS was 6 weeks and median survival till follow-up was 55.3 months (0–130 months). 33/42 patients underwent TIPS prior to 2013, their median survival till follow-up was 64.2 months.Conclusion: Our results validate the role of TIPS in the management of patients with BCS. With the accessibility of TIPS, requirement for liver transplantation has become rare. Background & Aims: Budd–Chiari syndrome (BCS) is an uncommon disorder defined as a hepatic venous outflow obstruction at any level between the hepatic veins and the right atrium. It usually involves thrombosis of the hepatic veins and/or the intrahepatic or suprahepatic inferior vena cava. Treatment of BCS includes medical, interventional radiological (TIPS) and surgical interventions. As the disease is rare, there is limited data regarding the long term survival of patients undergoing TIPS. The aim of this study was to report our single centre long term follow-up results of patients with BCS who underwent TIPS. Methods: 42 BCS patients underwent TIPS with covered stent between 2004 and 2014. Retrospective analysis was performed regarding the presenting symptoms and laboratory workup pre- and post-TIPS, etiology of BCS, extent of thrombosis, status of varices, therapeutic interventions, complications, symptom relief and overall outcome. Results: 16 women and 26 men with a mean age of 40 years (range: 14–60 years) at time of diagnosis were included. Myeloproliferative disorder and JAK 2 mutation were the commonest etiology followed by MTHFR mutation. The cause of BCS was unclear in 24 patients. There was significant improvement in ascites, GI bleed, HRS and transaminase levels post TIPS. 3 patients required a TIPS plasty and one patient underwent TIPS reduction. There were 11 deaths over the follow-up period, 4 within one month, 2 within six months and the rest after 3 years following TIPS. Median duration from clinical presentation to TIPS was 6 weeks and median survival till follow-up was 55.3 months (0–130 months). 33/42 patients underwent TIPS prior to 2013, their median survival till follow-up was 64.2 months. Conclusion: Our results validate the role of TIPS in the management of patients with BCS. With the accessibility of TIPS, requirement for liver transplantation has become rare." @default.
• W4235288735 created "2022-05-12" @default.
• W4235288735 creator A5013950586 @default.
• W4235288735 creator A5083919007 @default.
• W4235288735 date "2015-06-01" @default.
• W4235288735 modified "2023-10-16" @default.
• W4235288735 title "Long Term Survival of Patients Undergoing Tips in Budd–Chiari Syndrome" @default.
• W4235288735 doi "https://doi.org/10.1016/j.jceh.2015.07.105" @default.
• W4235288735 hasPublicationYear "2015" @default.
• W4235288735 type Work @default.
• W4235288735 citedByCount "1" @default.
• W4235288735 countsByYear W42352887352018 @default.
• W4235288735 crossrefType "journal-article" @default.
• W4235288735 hasAuthorship W4235288735A5013950586 @default.
• W4235288735 hasAuthorship W4235288735A5083919007 @default.
• W4235288735 hasConcept C126322002 @default.
• W4235288735 hasConcept C137627325 @default.
• W4235288735 hasConcept C141071460 @default.
• W4235288735 hasConcept C167135981 @default.
• W4235288735 hasConcept C2776208725 @default.
• W4235288735 hasConcept C2777214474 @default.
• W4235288735 hasConcept C2778555097 @default.
• W4235288735 hasConcept C2778800853 @default.
• W4235288735 hasConcept C2778808290 @default.
• W4235288735 hasConcept C2780011451 @default.
• W4235288735 hasConcept C2780496750 @default.
• W4235288735 hasConcept C2780868729 @default.
• W4235288735 hasConcept C2910216633 @default.
• W4235288735 hasConcept C71924100 @default.
• W4235288735 hasConceptScore W4235288735C126322002 @default.
• W4235288735 hasConceptScore W4235288735C137627325 @default.
• W4235288735 hasConceptScore W4235288735C141071460 @default.
• W4235288735 hasConceptScore W4235288735C167135981 @default.
• W4235288735 hasConceptScore W4235288735C2776208725 @default.
• W4235288735 hasConceptScore W4235288735C2777214474 @default.
• W4235288735 hasConceptScore W4235288735C2778555097 @default.
• W4235288735 hasConceptScore W4235288735C2778800853 @default.
• W4235288735 hasConceptScore W4235288735C2778808290 @default.
• W4235288735 hasConceptScore W4235288735C2780011451 @default.
• W4235288735 hasConceptScore W4235288735C2780496750 @default.
• W4235288735 hasConceptScore W4235288735C2780868729 @default.
• W4235288735 hasConceptScore W4235288735C2910216633 @default.
• W4235288735 hasConceptScore W4235288735C71924100 @default.
• W4235288735 hasLocation W42352887351 @default.
• W4235288735 hasOpenAccess W4235288735 @default.
• W4235288735 hasPrimaryLocation W42352887351 @default.
• W4235288735 hasRelatedWork W1508817574 @default.
• W4235288735 hasRelatedWork W177903144 @default.
• W4235288735 hasRelatedWork W2008825581 @default.
• W4235288735 hasRelatedWork W2089294546 @default.
• W4235288735 hasRelatedWork W2135083203 @default.
• W4235288735 hasRelatedWork W2411965116 @default.
• W4235288735 hasRelatedWork W2440400500 @default.
• W4235288735 hasRelatedWork W2914339860 @default.
• W4235288735 hasRelatedWork W2977502053 @default.
• W4235288735 hasRelatedWork W2979078041 @default.
• W4235288735 hasVolume "5" @default.
• W4235288735 isParatext "false" @default.
• W4235288735 isRetracted "false" @default.
• W4235288735 workType "article" @default.