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- W4235347991 abstract "The last years have witnessed important technological advances in cardiac radionuclide imaging driving research and clinical use and highlighting the potential of the technique for future applications. Among many fields under development, hardware design for dedicated small-footprint cardiac single-photon emission computed tomography (SPECT) scanners has made a huge leap forward. Particularly, the introduction of novel solid-state detector material (cadmium–zinc–telluride alloys) has improved detector sensitivity, reduced signal loss, enhanced spatial and energy resolution, and has opened avenues for novel ultrafast or low-dose imaging protocols. Positron emission tomography (PET) offers some advantages over SPECT with regard to spatial resolution and attenuation correction. Additionally, it allows the calculation of myocardial blood flow in tissue (in mL/min/g), which has emerged as a powerful marker of cardiovascular risk with incremental predictive value over traditional risk markers, perfusion variables, and ejection fraction. Moreover, hybrid PET/CT imaging allows a comprehensive assessment of coronary artery disease by a combination of anatomo-functional information. Recently, PET/magnetic resonance imaging has entered the clinical arena with the first fully integrated scanners now being commercially available. However, the clinical value of this promising technology has yet to be explored. Finally, the use of radionuclide imaging for molecular imaging allows ultraprecise targeting of culprit cells or molecules underlying pathophysiological processes of disease and, in the future, may possibly facilitate targeted delivery of bioengineered therapeutic nanoparticles." @default.
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- W4235347991 date "2018-07-01" @default.
- W4235347991 modified "2023-09-26" @default.
- W4235347991 title "Future potential" @default.
- W4235347991 doi "https://doi.org/10.1093/med/9780198784906.003.0129" @default.
- W4235347991 hasPublicationYear "2018" @default.
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