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- W4235508045 abstract "Objective: To assess the sequelae of temporary coronary artery occlusion in off-pump, beating heart CABG, i.e. ischemia, hemodynamic instability and the need for conversion to cardiopulmonary bypass. Methods: In 200 patients (150 male), mean age 60 (range 35–81) years, 365 distal anastomoses were performed, i.e. 1.8 anastomoses per patient through limited and full access. Onehundredseventysix LAD, 61 diagonal, 71 RCA, 7 RPD and 50 circumflex branches were grafted. Patients were pretreated with calcium antagonists, long-acting β-blockade and had thoracic epidural blockade. The anastomosis was constructed using two microvascular clamps, preceded by ischemic preconditioning in non-occlusive disease. Myocardial ischemia was defined as >1 mm S—T segment elevation. A simple aorto-coronary shunt, consisting of two intravenous catheters and a 10 cm connecting tube (flow>20 ml/min), was used in critical ischemia. Results: Ischemia occurred during 35 (10%) temporary coronary artery occlusions. Fifteen of these (43%) were RCA. In five of these 15 patients, all with non-occlusive disease, critical ischemia occurred with bradycardia, third-degree heart block and subsequently severe hypotension, which normally requires conversion to cardio-pulmonary bypass. Following introduction of the shunt (4 patients) electrocardiographic and hemodynamic parameters normalized within 30 s. The off-pump procedures could be continued uneventfully. There were no peri-operative infarctions. Conclusion: Temporary segmental occlusion is an effective method for anastomosis suturing in off-pump, beating heart CABG. Critical ischemia was observed rarely, only in the RCA and in non-occlusive disease. Temporary aorto-coronary shunting could avoid conversion to cardiopulmonary bypass and myocardial infarction." @default.
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- W4235508045 date "1999-11-01" @default.
- W4235508045 modified "2023-10-16" @default.
- W4235508045 title "When and how to shunt the coronary circulation in off-pump coronary artery bypass grafting" @default.
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- W4235508045 doi "https://doi.org/10.1093/ejcts/16.supplement_2.s2" @default.
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